Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation

Hansen Lui, Jiasheng Zhang, Stefanie R. Makinson, Michelle K. Cahill, Kevin W. Kelley, Hsin Yi Huang, Yulei Shang, Michael C. Oldham, Lauren Herl Martens, Fuying Gao, Giovanni Coppola, Steven A. Sloan, Christine L. Hsieh, Charles C. Kim, Eileen H. Bigio, Sandra Weintraub, Marek Marsel Mesulam, Rosa Rademakers, Ian R. MacKenzie, William W. SeeleyAnna Karydas, Bruce L. Miller, Barbara Borroni, Roberta Ghidoni, Robert V. Farese, Jeanne T. Paz, Ben A. Barres, Eric J. Huang*

*Corresponding author for this work

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Neuroscience