Progressive Multifocal Leukoencephalopathy

Elena Grebenciucova*, Joseph R. Berger

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations

Abstract

Progressive multifocal leukoencephalopathy (PML) is a rare opportunistic infection that occurs in patients whose immune system is compromised either because of an underlying illness or an immunosuppressive medication. John Cunningham virus, prevalent in 60% or more of the adult population as a latent or persistent infection, is responsible for the syndrome of PML. This article reviews PML in association with the most common immunotherapies and discusses risk mitigation and monitoring strategies.

Original languageEnglish (US)
Pages (from-to)739-750
Number of pages12
JournalNeurologic clinics
Volume36
Issue number4
DOIs
StatePublished - Nov 2018

Keywords

  • John Cunningham virus
  • Opportunistic infection
  • Progressive multifocal leukoencephalopathy

ASJC Scopus subject areas

  • Clinical Neurology

Fingerprint Dive into the research topics of 'Progressive Multifocal Leukoencephalopathy'. Together they form a unique fingerprint.

Cite this