Progressive Multifocal Leukoencephalopathy

Elena Grebenciucova; Joseph R. Berger

doi:10.1016/j.ncl.2018.06.002

Progressive Multifocal Leukoencephalopathy

Elena Grebenciucova^*, Joseph R. Berger

^*Corresponding author for this work

Neurology

Research output: Contribution to journal › Review article › peer-review

27 Scopus citations

Abstract

Progressive multifocal leukoencephalopathy (PML) is a rare opportunistic infection that occurs in patients whose immune system is compromised either because of an underlying illness or an immunosuppressive medication. John Cunningham virus, prevalent in 60% or more of the adult population as a latent or persistent infection, is responsible for the syndrome of PML. This article reviews PML in association with the most common immunotherapies and discusses risk mitigation and monitoring strategies.

Original language	English (US)
Pages (from-to)	739-750
Number of pages	12
Journal	Neurologic clinics
Volume	36
Issue number	4
DOIs	https://doi.org/10.1016/j.ncl.2018.06.002
State	Published - Nov 2018

Keywords

John Cunningham virus
Opportunistic infection
Progressive multifocal leukoencephalopathy

ASJC Scopus subject areas

Clinical Neurology

Access to Document

10.1016/j.ncl.2018.06.002

Cite this

@article{19c64230086c4b429d6a2669b3e70b92,

title = "Progressive Multifocal Leukoencephalopathy",

abstract = "Progressive multifocal leukoencephalopathy (PML) is a rare opportunistic infection that occurs in patients whose immune system is compromised either because of an underlying illness or an immunosuppressive medication. John Cunningham virus, prevalent in 60\% or more of the adult population as a latent or persistent infection, is responsible for the syndrome of PML. This article reviews PML in association with the most common immunotherapies and discusses risk mitigation and monitoring strategies.",

keywords = "John Cunningham virus, Opportunistic infection, Progressive multifocal leukoencephalopathy",

author = "Elena Grebenciucova and Berger, \{Joseph R.\}",

year = "2018",

month = nov,

doi = "10.1016/j.ncl.2018.06.002",

language = "English (US)",

volume = "36",

pages = "739--750",

journal = "Neurologic clinics",

issn = "0733-8619",

publisher = "W.B. Saunders",

number = "4",

}

TY - JOUR

T1 - Progressive Multifocal Leukoencephalopathy

AU - Grebenciucova, Elena

AU - Berger, Joseph R.

PY - 2018/11

Y1 - 2018/11

N2 - Progressive multifocal leukoencephalopathy (PML) is a rare opportunistic infection that occurs in patients whose immune system is compromised either because of an underlying illness or an immunosuppressive medication. John Cunningham virus, prevalent in 60% or more of the adult population as a latent or persistent infection, is responsible for the syndrome of PML. This article reviews PML in association with the most common immunotherapies and discusses risk mitigation and monitoring strategies.

AB - Progressive multifocal leukoencephalopathy (PML) is a rare opportunistic infection that occurs in patients whose immune system is compromised either because of an underlying illness or an immunosuppressive medication. John Cunningham virus, prevalent in 60% or more of the adult population as a latent or persistent infection, is responsible for the syndrome of PML. This article reviews PML in association with the most common immunotherapies and discusses risk mitigation and monitoring strategies.

KW - John Cunningham virus

KW - Opportunistic infection

KW - Progressive multifocal leukoencephalopathy

UR - https://www.scopus.com/pages/publications/85055272376

UR - https://www.scopus.com/inward/citedby.url?scp=85055272376&partnerID=8YFLogxK

U2 - 10.1016/j.ncl.2018.06.002

DO - 10.1016/j.ncl.2018.06.002

M3 - Review article

C2 - 30366552

AN - SCOPUS:85055272376

SN - 0733-8619

VL - 36

SP - 739

EP - 750

JO - Neurologic clinics

JF - Neurologic clinics

IS - 4

ER -

Progressive Multifocal Leukoencephalopathy

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this