Projection structure of a gap junction membrane channel at 7 Å resolution

V. M. Unger; N. M. Kumar; N. B. Gilula; M. Yeager

doi:10.1038/nsb0197-39

Projection structure of a gap junction membrane channel at 7 Å resolution

V. M. Unger, N. M. Kumar, N. B. Gilula, M. Yeager^*

^*Corresponding author for this work

Molecular Biosciences

Research output: Contribution to journal › Article › peer-review

107 Scopus citations

Abstract

Electron cryo-microscopy and image analysis of frozen-hydrated, two- dimensional crystals of gap junction membrane channels formed by recombinant α₁ connexin (Cx43) reveal a ring of transmembrane α-helices that lines the aqueous pore and a second ring of α-helices in close contact with the membrane lipids.

Original language	English (US)
Pages (from-to)	39-43
Number of pages	5
Journal	Nature Structural Biology
Volume	4
Issue number	1
DOIs	https://doi.org/10.1038/nsb0197-39
State	Published - Jan 18 1997

ASJC Scopus subject areas

Biochemistry
Structural Biology
Genetics

Access to Document

10.1038/nsb0197-39

Cite this

@article{de0403daf4c34d79aed50f3ec4473d56,

title = "Projection structure of a gap junction membrane channel at 7 {\AA} resolution",

abstract = "Electron cryo-microscopy and image analysis of frozen-hydrated, two- dimensional crystals of gap junction membrane channels formed by recombinant α1 connexin (Cx43) reveal a ring of transmembrane α-helices that lines the aqueous pore and a second ring of α-helices in close contact with the membrane lipids.",

author = "Unger, {V. M.} and Kumar, {N. M.} and Gilula, {N. B.} and M. Yeager",

year = "1997",

month = jan,

day = "18",

doi = "10.1038/nsb0197-39",

language = "English (US)",

volume = "4",

pages = "39--43",

journal = "Nature Structural Biology",

issn = "1072-8368",

publisher = "Nature Publishing Group",

number = "1",

}

TY - JOUR

T1 - Projection structure of a gap junction membrane channel at 7 Å resolution

AU - Unger, V. M.

AU - Kumar, N. M.

AU - Gilula, N. B.

AU - Yeager, M.

PY - 1997/1/18

Y1 - 1997/1/18

N2 - Electron cryo-microscopy and image analysis of frozen-hydrated, two- dimensional crystals of gap junction membrane channels formed by recombinant α1 connexin (Cx43) reveal a ring of transmembrane α-helices that lines the aqueous pore and a second ring of α-helices in close contact with the membrane lipids.

AB - Electron cryo-microscopy and image analysis of frozen-hydrated, two- dimensional crystals of gap junction membrane channels formed by recombinant α1 connexin (Cx43) reveal a ring of transmembrane α-helices that lines the aqueous pore and a second ring of α-helices in close contact with the membrane lipids.

UR - http://www.scopus.com/inward/record.url?scp=0031024656&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0031024656&partnerID=8YFLogxK

U2 - 10.1038/nsb0197-39

DO - 10.1038/nsb0197-39

M3 - Article

C2 - 8989321

AN - SCOPUS:0031024656

SN - 1072-8368

VL - 4

SP - 39

EP - 43

JO - Nature Structural Biology

JF - Nature Structural Biology

IS - 1

ER -

Projection structure of a gap junction membrane channel at 7 Å resolution

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this