Prolactin-secreting tumors: What's new?

Mark E Molitch*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

14 Scopus citations

Abstract

Prolactinomas are a common cause of reproductive/sexual dysfunction. Once other causes of hyperprolactinemia have been excluded with a careful history and physical examination, routine chemistries, a perganncy test and a thyriod-stimulating hormone, imaging with magnetic resonance imaging or computed tomography will delineate the size and extent of the tumor. Medical theraphy with cabergoline or bromocriptine is the initial treatment of choice. When infertility is the primary indication for treatment, bromocriptine use has an extensive safety experience and is preferred by some clinicians. However, for other indications, cabergoline appears to be more efficacious and better tolerated. Transsphenoidal surgery remains an option, especially for patients with microadenomas, when medical therapy is ineffective or not tolerated.

Original languageEnglish (US)
JournalExpert Review of Anticancer Therapy
Volume6
Issue number9 SUPPL.
DOIs
StatePublished - Sep 1 2006

Keywords

  • Bromocriptine
  • Cabergoline
  • Pituitary tumor
  • Prolactin
  • Prolactinoma

ASJC Scopus subject areas

  • Oncology
  • Pharmacology (medical)

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