PROMIS® Adult Health Profiles

Efficient Short-Form Measures of Seven Health Domains

David Cella*, Seung W. Choi, David M. Condon, Benjamin David Schalet, Ron D. Hays, Nan E Rothrock, Susan Yount, Karon Frances Cook, Richard Gershon, Dagmar Amtmann, Darren A. DeWalt, Paul A. Pilkonis, Arthur A. Stone, Kevin Weinfurt, Bryce B. Reeve

*Corresponding author for this work

Research output: Contribution to journalArticle

Abstract

Background: There is a need for valid self-report measures of core health-related quality of life (HRQoL) domains. Objective: To derive brief, reliable and valid health profile measures from the Patient Reported Outcomes Measurement Information System® (PROMIS®) item banks. Methods: Literature review, investigator consensus process, item response theory (IRT) analysis, and expert review of scaling results from multiple PROMIS data sets. We developed 3 profile measures ranging in length from 29 to 57 questions. These profiles assess important HRQoL domains with highly informative subsets of items from respective item banks and yield reliable information across mild-to-severe levels of HRQoL experiences. Each instrument assesses the domains of pain interference, fatigue, depression, anxiety, sleep disturbance, physical function, and social function using 4-, 6-, and 8-item short forms for each domain, and an average pain intensity domain score, using a 0-10 numeric rating scale. Results: With few exceptions, all domain short forms within the profile measures were highly reliable across at least 3 standard deviation (30 T-score) units and were strongly correlated with the full bank scores. Construct validity with ratings of general health and quality of life was demonstrated. Information to inform statistical power for clinical and general population samples is also provided. Conclusions: Although these profile measures have been used widely, with summary scoring routines published, description of their development, reliability, and initial validity has not been published until this article. Further evaluation of these measures and clinical applications are encouraged.

Original languageEnglish (US)
Pages (from-to)537-544
Number of pages8
JournalValue in Health
Volume22
Issue number5
DOIs
StatePublished - May 1 2019

Fingerprint

Health Information Systems
Quality of Life
Health
Information Systems
Pain
Life Change Events
Reproducibility of Results
Self Report
Health Status
Fatigue
Consensus
Sleep
Anxiety
Research Personnel
Depression
Patient Reported Outcome Measures
Population

Keywords

  • PROMIS®
  • health-related quality of life
  • information system
  • patient-reported outcome measurement

ASJC Scopus subject areas

  • Health Policy
  • Public Health, Environmental and Occupational Health

Cite this

Cella, David ; Choi, Seung W. ; Condon, David M. ; Schalet, Benjamin David ; Hays, Ron D. ; Rothrock, Nan E ; Yount, Susan ; Cook, Karon Frances ; Gershon, Richard ; Amtmann, Dagmar ; DeWalt, Darren A. ; Pilkonis, Paul A. ; Stone, Arthur A. ; Weinfurt, Kevin ; Reeve, Bryce B. / PROMIS® Adult Health Profiles : Efficient Short-Form Measures of Seven Health Domains. In: Value in Health. 2019 ; Vol. 22, No. 5. pp. 537-544.
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abstract = "Background: There is a need for valid self-report measures of core health-related quality of life (HRQoL) domains. Objective: To derive brief, reliable and valid health profile measures from the Patient Reported Outcomes Measurement Information System{\circledR} (PROMIS{\circledR}) item banks. Methods: Literature review, investigator consensus process, item response theory (IRT) analysis, and expert review of scaling results from multiple PROMIS data sets. We developed 3 profile measures ranging in length from 29 to 57 questions. These profiles assess important HRQoL domains with highly informative subsets of items from respective item banks and yield reliable information across mild-to-severe levels of HRQoL experiences. Each instrument assesses the domains of pain interference, fatigue, depression, anxiety, sleep disturbance, physical function, and social function using 4-, 6-, and 8-item short forms for each domain, and an average pain intensity domain score, using a 0-10 numeric rating scale. Results: With few exceptions, all domain short forms within the profile measures were highly reliable across at least 3 standard deviation (30 T-score) units and were strongly correlated with the full bank scores. Construct validity with ratings of general health and quality of life was demonstrated. Information to inform statistical power for clinical and general population samples is also provided. Conclusions: Although these profile measures have been used widely, with summary scoring routines published, description of their development, reliability, and initial validity has not been published until this article. Further evaluation of these measures and clinical applications are encouraged.",
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author = "David Cella and Choi, {Seung W.} and Condon, {David M.} and Schalet, {Benjamin David} and Hays, {Ron D.} and Rothrock, {Nan E} and Susan Yount and Cook, {Karon Frances} and Richard Gershon and Dagmar Amtmann and DeWalt, {Darren A.} and Pilkonis, {Paul A.} and Stone, {Arthur A.} and Kevin Weinfurt and Reeve, {Bryce B.}",
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Cella, D, Choi, SW, Condon, DM, Schalet, BD, Hays, RD, Rothrock, NE, Yount, S, Cook, KF, Gershon, R, Amtmann, D, DeWalt, DA, Pilkonis, PA, Stone, AA, Weinfurt, K & Reeve, BB 2019, 'PROMIS® Adult Health Profiles: Efficient Short-Form Measures of Seven Health Domains', Value in Health, vol. 22, no. 5, pp. 537-544. https://doi.org/10.1016/j.jval.2019.02.004

PROMIS® Adult Health Profiles : Efficient Short-Form Measures of Seven Health Domains. / Cella, David; Choi, Seung W.; Condon, David M.; Schalet, Benjamin David; Hays, Ron D.; Rothrock, Nan E; Yount, Susan; Cook, Karon Frances; Gershon, Richard; Amtmann, Dagmar; DeWalt, Darren A.; Pilkonis, Paul A.; Stone, Arthur A.; Weinfurt, Kevin; Reeve, Bryce B.

In: Value in Health, Vol. 22, No. 5, 01.05.2019, p. 537-544.

Research output: Contribution to journalArticle

TY - JOUR

T1 - PROMIS® Adult Health Profiles

T2 - Efficient Short-Form Measures of Seven Health Domains

AU - Cella, David

AU - Choi, Seung W.

AU - Condon, David M.

AU - Schalet, Benjamin David

AU - Hays, Ron D.

AU - Rothrock, Nan E

AU - Yount, Susan

AU - Cook, Karon Frances

AU - Gershon, Richard

AU - Amtmann, Dagmar

AU - DeWalt, Darren A.

AU - Pilkonis, Paul A.

AU - Stone, Arthur A.

AU - Weinfurt, Kevin

AU - Reeve, Bryce B.

PY - 2019/5/1

Y1 - 2019/5/1

N2 - Background: There is a need for valid self-report measures of core health-related quality of life (HRQoL) domains. Objective: To derive brief, reliable and valid health profile measures from the Patient Reported Outcomes Measurement Information System® (PROMIS®) item banks. Methods: Literature review, investigator consensus process, item response theory (IRT) analysis, and expert review of scaling results from multiple PROMIS data sets. We developed 3 profile measures ranging in length from 29 to 57 questions. These profiles assess important HRQoL domains with highly informative subsets of items from respective item banks and yield reliable information across mild-to-severe levels of HRQoL experiences. Each instrument assesses the domains of pain interference, fatigue, depression, anxiety, sleep disturbance, physical function, and social function using 4-, 6-, and 8-item short forms for each domain, and an average pain intensity domain score, using a 0-10 numeric rating scale. Results: With few exceptions, all domain short forms within the profile measures were highly reliable across at least 3 standard deviation (30 T-score) units and were strongly correlated with the full bank scores. Construct validity with ratings of general health and quality of life was demonstrated. Information to inform statistical power for clinical and general population samples is also provided. Conclusions: Although these profile measures have been used widely, with summary scoring routines published, description of their development, reliability, and initial validity has not been published until this article. Further evaluation of these measures and clinical applications are encouraged.

AB - Background: There is a need for valid self-report measures of core health-related quality of life (HRQoL) domains. Objective: To derive brief, reliable and valid health profile measures from the Patient Reported Outcomes Measurement Information System® (PROMIS®) item banks. Methods: Literature review, investigator consensus process, item response theory (IRT) analysis, and expert review of scaling results from multiple PROMIS data sets. We developed 3 profile measures ranging in length from 29 to 57 questions. These profiles assess important HRQoL domains with highly informative subsets of items from respective item banks and yield reliable information across mild-to-severe levels of HRQoL experiences. Each instrument assesses the domains of pain interference, fatigue, depression, anxiety, sleep disturbance, physical function, and social function using 4-, 6-, and 8-item short forms for each domain, and an average pain intensity domain score, using a 0-10 numeric rating scale. Results: With few exceptions, all domain short forms within the profile measures were highly reliable across at least 3 standard deviation (30 T-score) units and were strongly correlated with the full bank scores. Construct validity with ratings of general health and quality of life was demonstrated. Information to inform statistical power for clinical and general population samples is also provided. Conclusions: Although these profile measures have been used widely, with summary scoring routines published, description of their development, reliability, and initial validity has not been published until this article. Further evaluation of these measures and clinical applications are encouraged.

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KW - patient-reported outcome measurement

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