Propranolol treatment of infantile hemangiomas: Anticipatory guidance for parents and caretakers

Kari Martin*, Francine Bleib, Sarah L. Chamlin, Yvonne E. Chiu, Ilona J. Frieden, Peter C. Frommelt, Maria C. Garzon, Eun Kyung M. Kwon, Susan MacLellan-Tobert, Anthony J. Mancini, Marcia Seefeldt, Robert Sidbury, Dawn H. Siegel, Beth A. Drolet, Robert J. Boucek

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

Infantile hemangiomas (IH) are benign tumors of endothelial-like cells. Occurring in 4.5% of children, they are the most common tumor of childhood. The great majority of patients with IH will not need treatment, but 10% require systemic treatment. Many treatments have been described for the treatment of IH, but the Food and Drug Administration has not approved any. Over the last decade, numerous reports of successful treatment of IH with propranolol have been published. Despite its widespread use, little is known regarding the proper dosing, safety monitoring, and during of treatment or long-term outcomes for propranolol treatment of IH. Given its potential side effects, detailed education regarding proper administration of the medication as well as warning signs to watch for is necessary for parents and caretakers. Herein, we provide a parental handout that practitioners can individually tailor for use in their clinics when educating parents and caretakers about the use of propranolol for IH. Updates will also need to be made as more is learned regarding the optimal dosing and safety monitoring when using propranolol for this indication.

Original languageEnglish (US)
Pages (from-to)155-159
Number of pages5
JournalPediatric dermatology
Volume30
Issue number1
DOIs
StatePublished - Jan 2013

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Dermatology

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