ProSight PTM 2.0: Improved protein identification and characterization for top down mass spectrometry

Leonid Zamdborg, Richard D. LeDuc*, Kevin J. Glowacz, Yong Bin Kim, Vinayak Viswanathan, Ian T. Spaulding, Bryan P. Early, Eric J. Bluhm, Shannee Babai, Neil L. Kelleher

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

170 Scopus citations

Abstract

ProSight PTM 2.0 (http://prosightptm2.scs.uiuc.edu) is the next generation of the ProSight PTM webbased system for the identification and characterization of proteins using top down tandem mass spectrometry. It introduces an entirely new datadriven interface, integrated Sequence Gazer for protein characterization, support for fixed modifications, terminal modifications and improved support for multiple precursor ions (multiplexing). Furthermore, it supports data import and export for local analysis and collaboration.

Original languageEnglish (US)
Pages (from-to)W701-W706
JournalNucleic acids research
Volume35
Issue numberSUPPL.2
DOIs
StatePublished - Jul 2007

ASJC Scopus subject areas

  • Genetics

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