Protecting against cerebrovascular injury: Contributions of 12/15-lipoxygenase to edema formation after transient focal ischemia

Keyphrases

• Cerebrovascular Accident 100%
• Edema Formation 100%
• 12/15-Lipoxygenase 100%
• Transient Focal Ischemia 100%
• Lipoxygenase Inhibitors 40%
• Baicalin 30%
• Hypoxia 20%
• Transient Middle Cerebral Artery Occlusion (tMCAO) 20%
• Immunoglobulin G 20%
• Claudin-5 20%
• Peri-infarct Area 20%
• Wild Mice 10%
• Immunohistochemistry 10%
• Endothelial Cells 10%
• Knock-in Mouse Model 10%
• Hydrogen Peroxide 10%
• Cell Culture 10%
• Tight Junction Proteins 10%
• Neurovascular Unit 10%
• Vascular Injury 10%
• Ischemia-reperfusion Injury 10%
• Brain Parenchyma 10%
• Detrimental Effects 10%
• Brain Endothelial Cells 10%
• Brain Injury 10%
• Neuroprotection 10%
• Neuronal Cell Death 10%
• 5-lipoxygenase (5-LOX) 10%
• Gene Knockout 10%
• Neuron Cells 10%
• Water Content 10%
• Edema 10%
• Neuroprotectant 10%
• 15-lipoxygenase (15-LOX) 10%
• Endothelial Cell Line 10%
• Weighting Method 10%
• Ischemic Brain 10%
• Brain Edema 10%
• Focal Ischemia 10%
• Brain Microvessels 10%
• Human Brain Microvascular Endothelial Cells (HBMEC) 10%
• Gene Treatment 10%
• Lipoxygenase Gene 10%
• H2O2-induced Oxidative Stress 10%
• Brain Vasculature 10%
• Brain Hemispheres 10%
• Ischemic Brain Damage 10%

Neuroscience

• Arachidonate 15 Lipoxygenase 100%
• Cerebrovascular Accident 100%
• Ischemia 100%
• Lipoxygenase Inhibitor 50%
• Baicalein 30%
• Immunoglobulin G 20%
• Hydrogen Peroxide 20%
• Claudin 5 20%
• Middle Cerebral Artery 20%
• In Vivo 10%
• Cell Line 10%
• Neuronal Cell Death 10%
• Neuroprotection 10%
• Tight Junction Protein 10%
• Oxidative Stress 10%
• Immunohistochemistry 10%
• Microvessel 10%
• Parenchyma 10%
• Cell Culture 10%
• Gene Knockout 10%