Protecting the Kidney in Liver Transplant Candidates: Practice-Based Recommendations From the American Society of Transplantation Liver and Intestine Community of Practice

J. G. O'Leary*, Josh Levitsky, F. Wong, M. K. Nadim, M. Charlton, W. R. Kim

*Corresponding author for this work

Research output: Contribution to journalReview article

14 Citations (Scopus)

Abstract

Acute kidney injury (AKI) and chronic kidney disease (CKD) are common in patients awaiting liver transplantation, and both have a marked impact on the perioperative and long-term morbidity and mortality of liver transplant recipients. Consequently, we reviewed the epidemiology of AKI and CKD in patients with end-stage liver disease, highlighted strategies to prevent and manage AKI, evaluated the changing liver transplant waiting list's impact on kidney function, delineated important considerations in simultaneous liver–kidney transplant selection, and projected possible future transplant policy changes and outcomes. This review was assembled by experts in the field and endorsed by the American Society of Transplantation Liver and Intestinal Community of Practice and Board of Directors and provides practice-based recommendations for preservation of kidney function in patients with end-stage liver disease.

Original languageEnglish (US)
Pages (from-to)2516-2531
Number of pages16
JournalAmerican Journal of Transplantation
Volume16
Issue number9
DOIs
StatePublished - Sep 1 2016

Fingerprint

Acute Kidney Injury
Intestines
End Stage Liver Disease
Transplants
Chronic Renal Insufficiency
Kidney
Liver
Waiting Lists
Liver Transplantation
Epidemiology
Morbidity
Mortality

Keywords

  • clinical research/practice
  • glomerular filtration rate (GFR)
  • kidney (native) function/dysfunction
  • kidney disease
  • kidney transplantation/nephrology
  • liver transplantation/hepatology
  • translational research/science

ASJC Scopus subject areas

  • Immunology and Allergy
  • Transplantation
  • Pharmacology (medical)

Cite this

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title = "Protecting the Kidney in Liver Transplant Candidates: Practice-Based Recommendations From the American Society of Transplantation Liver and Intestine Community of Practice",
abstract = "Acute kidney injury (AKI) and chronic kidney disease (CKD) are common in patients awaiting liver transplantation, and both have a marked impact on the perioperative and long-term morbidity and mortality of liver transplant recipients. Consequently, we reviewed the epidemiology of AKI and CKD in patients with end-stage liver disease, highlighted strategies to prevent and manage AKI, evaluated the changing liver transplant waiting list's impact on kidney function, delineated important considerations in simultaneous liver–kidney transplant selection, and projected possible future transplant policy changes and outcomes. This review was assembled by experts in the field and endorsed by the American Society of Transplantation Liver and Intestinal Community of Practice and Board of Directors and provides practice-based recommendations for preservation of kidney function in patients with end-stage liver disease.",
keywords = "clinical research/practice, glomerular filtration rate (GFR), kidney (native) function/dysfunction, kidney disease, kidney transplantation/nephrology, liver transplantation/hepatology, translational research/science",
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Protecting the Kidney in Liver Transplant Candidates : Practice-Based Recommendations From the American Society of Transplantation Liver and Intestine Community of Practice. / O'Leary, J. G.; Levitsky, Josh; Wong, F.; Nadim, M. K.; Charlton, M.; Kim, W. R.

In: American Journal of Transplantation, Vol. 16, No. 9, 01.09.2016, p. 2516-2531.

Research output: Contribution to journalReview article

TY - JOUR

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T2 - Practice-Based Recommendations From the American Society of Transplantation Liver and Intestine Community of Practice

AU - O'Leary, J. G.

AU - Levitsky, Josh

AU - Wong, F.

AU - Nadim, M. K.

AU - Charlton, M.

AU - Kim, W. R.

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Y1 - 2016/9/1

N2 - Acute kidney injury (AKI) and chronic kidney disease (CKD) are common in patients awaiting liver transplantation, and both have a marked impact on the perioperative and long-term morbidity and mortality of liver transplant recipients. Consequently, we reviewed the epidemiology of AKI and CKD in patients with end-stage liver disease, highlighted strategies to prevent and manage AKI, evaluated the changing liver transplant waiting list's impact on kidney function, delineated important considerations in simultaneous liver–kidney transplant selection, and projected possible future transplant policy changes and outcomes. This review was assembled by experts in the field and endorsed by the American Society of Transplantation Liver and Intestinal Community of Practice and Board of Directors and provides practice-based recommendations for preservation of kidney function in patients with end-stage liver disease.

AB - Acute kidney injury (AKI) and chronic kidney disease (CKD) are common in patients awaiting liver transplantation, and both have a marked impact on the perioperative and long-term morbidity and mortality of liver transplant recipients. Consequently, we reviewed the epidemiology of AKI and CKD in patients with end-stage liver disease, highlighted strategies to prevent and manage AKI, evaluated the changing liver transplant waiting list's impact on kidney function, delineated important considerations in simultaneous liver–kidney transplant selection, and projected possible future transplant policy changes and outcomes. This review was assembled by experts in the field and endorsed by the American Society of Transplantation Liver and Intestinal Community of Practice and Board of Directors and provides practice-based recommendations for preservation of kidney function in patients with end-stage liver disease.

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KW - glomerular filtration rate (GFR)

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KW - kidney disease

KW - kidney transplantation/nephrology

KW - liver transplantation/hepatology

KW - translational research/science

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