The protein coding assignments for each of the S genes of the avian reovirus S1133 have been determined. In vitro translation of RNA derived from individual S dsRNA genome segments demonstrated that the largest S gene, S1, codes for the smallest protein, σc; the σA for σA; the S3 gene for σC and the S4 gene for σNS. No other gene products could be identified. By examination of appropriate reassortant viruses, these assignments were confirmed.
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