Proteomics guided discovery of flavopeptins: Anti-proliferative aldehydes synthesized by a reductase domain-containing non-ribosomal peptide synthetase

Pharmacology, Toxicology and Pharmaceutical Science

• Aldehyde 100%
• Peptide 66%
• Proteasome 33%
• Proteinase 33%
• Streptomyces 33%
• Oxidoreductase 33%
• Nonribosomal Peptide Synthetase 33%
• Diseases 16%
• Enzyme 16%
• Lymphoma 16%
• Multiple Myeloma 16%
• Microorganism 16%
• Malignant Neoplasm 16%
• Natural Product 16%
• Proteinase Inhibitor 16%
• Cellular Processes 16%
• Antiproliferative Activity 16%
• Cysteine Proteinase 16%
• Papain 16%
• Calpain 16%
• Leupeptin 16%
• Lipopeptide 16%
• Chymostatin 16%
• Biological Activity 16%

INIS

• peptides 100%
• aldehydes 100%
• reductases 33%
• synthetases 33%
• streptomyces 33%
• cancer 16%
• humans 16%
• solids 16%
• screening 16%
• diseases 16%
• synthesis 16%
• genes 16%
• origin 16%
• metabolism 16%
• inhibition 16%
• screens 16%
• microorganisms 16%
• nad 16%
• enzymes 16%
• lymphomas 16%
• cysteine 16%
• verification 16%
• papain 16%

Biochemistry, Genetics and Molecular Biology

• Peptide 50%
• Proteasome 33%
• Reductase 33%
• Proteomics 33%
• Nonribosomal Peptide 33%
• Streptomyces 33%
• Protease 33%
• Development 16%
• C-Terminus 16%
• Biological Activity 16%
• Calpain 16%
• Screening 16%
• Gene Cluster 16%
• Protease Inhibitor 16%
• Lysozyme 16%
• Anabolism 16%
• Cysteine Protease 16%
• Papain 16%
• Peptide Synthesis 16%
• Solid 16%
• Lipopeptide 16%
• Leupeptin 16%
• Antiproliferative Activity 16%
• Secondary Metabolism 16%
• Species 16%
• Attention 16%