Proteopathic tau primes and activates interleukin-1β via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway

Shanya Jiang, Nicole M. Maphis, Jessica Binder, Devon Chisholm, Lea Weston, Walter Duran, Crina Peterson, Amber Zimmerman, Michael A. Mandell, Stephen D. Jett, Eileen Bigio, Changiz Geula, Nikolaos Mellios, Jason P. Weick, Gary A. Rosenberg, Eicke Latz, Michael T. Heneka, Kiran Bhaskar*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

54 Scopus citations

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Keyphrases

Medicine and Dentistry

Biochemistry, Genetics and Molecular Biology

Neuroscience

Immunology and Microbiology