Keyphrases
Selective Inhibitor
100%
Nociceptor
100%
Channel Blockage
100%
Action Potential Propagation
100%
Nav1.7 Sodium Channel
100%
ProTx-II
100%
Nav1.7
70%
Nav1.1
30%
125I
30%
Gain-of-function mutation
20%
IC50 Value
20%
Subtype Selectivity
20%
Recombinant
10%
Excitability
10%
Acute Pain
10%
Rodent Models
10%
Nerve
10%
Point mutation
10%
Voltage Gating
10%
Sodium
10%
Sensory Neurons
10%
High Affinity
10%
Human Genetics
10%
Channel Modulators
10%
Anticonvulsant
10%
Channelopathy
10%
Channel Blocker
10%
SCN9A
10%
HNav1.7
10%
Analgesic
10%
Beta-blockers
10%
Binding Assay
10%
Local Anesthetics
10%
Pain Signaling
10%
Genetic Evidence
10%
Selective Channels
10%
Compound Action Potential
10%
Cutaneous Nerve
10%
C-fiber
10%
Inflammatory Pain
10%
Painful Neuropathy
10%
A-fiber
10%
Human Genetic Data
10%
Tarantula Toxin
10%
Human Losses
10%
Venom Peptides
10%
Human Pain Model
10%
Medicine and Dentistry
Iodine 125
100%
Nociceptor
100%
Sodium Channel Nav1.7
100%
Action Potential
100%
Human Genetics
66%
IC50
66%
Loss of Function Mutation
33%
Point Mutation
33%
Excitability
33%
Binding Assay
33%
Anodyne
33%
Anticonvulsant
33%
Channel Blocker
33%
Neuropathy
33%
Pain
33%
Gain of Function Mutation
33%
Channelopathy
33%
Inflammatory Pain
33%
Channel Modulator
33%
Local Anesthetic
33%
Experimental Pain
33%
Neuroscience
Nociceptor
100%
Sodium Channel Nav1.7
100%
Action Potential
100%
Iodine-125
100%
Sensory Neuron
33%
Channel Blocker
33%
Cutaneous Nerve
33%
Point Mutation
33%
Excitability
33%
Loss of Function Mutation
33%
Gain of Function Mutation
33%
Channelopathy
33%
Anticonvulsant
33%
Neuropathy
33%
Immunology and Microbiology
Sodium Channel
100%
Action Potential
100%
Iodine-125
100%
Pain Receptor
100%
IC50
66%
Point Mutation
33%
Loss of Function Mutation
33%
Excitability
33%
Electric Potential
33%
Gain of Function Mutation
33%
Tarantula
33%
Biochemistry, Genetics and Molecular Biology
Nav1.7
100%
Action Potential
100%
Sodium Channel
100%
Pain Receptor
100%
Iodine-125
42%
Human Genetics
28%
IC50
28%
Venom Peptide
14%
Point Mutation
14%
Electric Potential
14%
Sensory Neuron
14%
Gain of Function Mutation
14%
Excitability
14%
Loss of Function Mutation
14%
Channel Blocker
14%
Tarantula
14%
Channelopathy
14%
Pharmacology, Toxicology and Pharmaceutical Science
Iodine-125
100%
Sodium Channel Nav1.7
100%
IC50
66%
Local Anesthetic Agent
33%
Channel Blocker
33%
Tarantula
33%
Pain
33%
Anticonvulsive Agent
33%
Analgesic Agent
33%
Neuropathy
33%
Inflammatory Pain
33%
Experimental Pain
33%
Channelopathy
33%