Pruritus in Cutaneous T-Cell Lymphoma and Its Management

Linda Serrano, Maria Estela Martinez-Escala, Xiaolong A. Zhou, Joan Guitart*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

15 Scopus citations


Pruritus is a common symptom in cutaneous T-cell lymphoma (CTCL) and critically affects the quality of life of patients. Understanding the pruritogenesis has led to development of new therapeutic agents with promising outcomes in management of this recalcitrant symptom. Clinical assessments are warranted to aid in evaluation of treatment response or disease recurrence. Severe pruritus scores may require further investigation of emotional distress for a better patient approach. Dermatologists play a key role in the treatment of CTCL-pruritus by guiding the patient in the importance of preserving the integrity of the skin barrier.

Original languageEnglish (US)
Pages (from-to)245-258
Number of pages14
JournalDermatologic clinics
Issue number3
StatePublished - Jul 2018


  • Antidepressants
  • Aprepitant
  • Cutaneous T-cell lymphoma
  • Histone deacetylase inhibitors
  • Interleukins
  • Pruritus
  • Substance P
  • Visual analog scale

ASJC Scopus subject areas

  • Dermatology


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