Pruritus in Cutaneous T-Cell Lymphoma and Its Management

Linda Serrano; Maria Estela Martinez-Escala; Xiaolong A. Zhou; Joan Guitart

doi:10.1016/j.det.2018.02.011

Pruritus in Cutaneous T-Cell Lymphoma and Its Management

Linda Serrano, Maria Estela Martinez-Escala, Xiaolong A. Zhou, Joan Guitart^*

^*Corresponding author for this work

Dermatology

Research output: Contribution to journal › Review article › peer-review

15 Scopus citations

Abstract

Pruritus is a common symptom in cutaneous T-cell lymphoma (CTCL) and critically affects the quality of life of patients. Understanding the pruritogenesis has led to development of new therapeutic agents with promising outcomes in management of this recalcitrant symptom. Clinical assessments are warranted to aid in evaluation of treatment response or disease recurrence. Severe pruritus scores may require further investigation of emotional distress for a better patient approach. Dermatologists play a key role in the treatment of CTCL-pruritus by guiding the patient in the importance of preserving the integrity of the skin barrier.

Original language	English (US)
Pages (from-to)	245-258
Number of pages	14
Journal	Dermatologic clinics
Volume	36
Issue number	3
DOIs	https://doi.org/10.1016/j.det.2018.02.011
State	Published - Jul 2018

Keywords

Antidepressants
Aprepitant
Cutaneous T-cell lymphoma
Histone deacetylase inhibitors
Interleukins
Pruritus
Substance P
Visual analog scale

ASJC Scopus subject areas

Dermatology

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10.1016/j.det.2018.02.011

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title = "Pruritus in Cutaneous T-Cell Lymphoma and Its Management",

abstract = "Pruritus is a common symptom in cutaneous T-cell lymphoma (CTCL) and critically affects the quality of life of patients. Understanding the pruritogenesis has led to development of new therapeutic agents with promising outcomes in management of this recalcitrant symptom. Clinical assessments are warranted to aid in evaluation of treatment response or disease recurrence. Severe pruritus scores may require further investigation of emotional distress for a better patient approach. Dermatologists play a key role in the treatment of CTCL-pruritus by guiding the patient in the importance of preserving the integrity of the skin barrier.",

keywords = "Antidepressants, Aprepitant, Cutaneous T-cell lymphoma, Histone deacetylase inhibitors, Interleukins, Pruritus, Substance P, Visual analog scale",

author = "Linda Serrano and Martinez-Escala, {Maria Estela} and Zhou, {Xiaolong A.} and Joan Guitart",

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language = "English (US)",

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T1 - Pruritus in Cutaneous T-Cell Lymphoma and Its Management

AU - Serrano, Linda

AU - Martinez-Escala, Maria Estela

AU - Zhou, Xiaolong A.

AU - Guitart, Joan

PY - 2018/7

Y1 - 2018/7

N2 - Pruritus is a common symptom in cutaneous T-cell lymphoma (CTCL) and critically affects the quality of life of patients. Understanding the pruritogenesis has led to development of new therapeutic agents with promising outcomes in management of this recalcitrant symptom. Clinical assessments are warranted to aid in evaluation of treatment response or disease recurrence. Severe pruritus scores may require further investigation of emotional distress for a better patient approach. Dermatologists play a key role in the treatment of CTCL-pruritus by guiding the patient in the importance of preserving the integrity of the skin barrier.

AB - Pruritus is a common symptom in cutaneous T-cell lymphoma (CTCL) and critically affects the quality of life of patients. Understanding the pruritogenesis has led to development of new therapeutic agents with promising outcomes in management of this recalcitrant symptom. Clinical assessments are warranted to aid in evaluation of treatment response or disease recurrence. Severe pruritus scores may require further investigation of emotional distress for a better patient approach. Dermatologists play a key role in the treatment of CTCL-pruritus by guiding the patient in the importance of preserving the integrity of the skin barrier.

KW - Antidepressants

KW - Aprepitant

KW - Cutaneous T-cell lymphoma

KW - Histone deacetylase inhibitors

KW - Interleukins

KW - Pruritus

KW - Substance P

KW - Visual analog scale

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AN - SCOPUS:85048881552

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JO - Dermatologic Clinics

JF - Dermatologic Clinics

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ER -

Pruritus in Cutaneous T-Cell Lymphoma and Its Management

Abstract

Keywords

ASJC Scopus subject areas

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