Psychological impact of recall in high-risk breast MRI screening

Suzanne M. O'Neill; Wendy S. Rubinstein; Stephen F. Sener; Scott M. Weissman; Anna C. Newlin; Daniel K. West; David B. Ecanow; Alfred W. Rademaker; Robert R. Edelman

doi:10.1007/s10549-008-0140-0

Psychological impact of recall in high-risk breast MRI screening

Suzanne M. O'Neill, Wendy S. Rubinstein, Stephen F. Sener, Scott M. Weissman, Anna C. Newlin, Daniel K. West, David B. Ecanow, Alfred W. Rademaker, Robert R. Edelman

Research output: Contribution to journal › Article › peer-review

19 Scopus citations

Abstract

Purpose To address the widespread concern that false-positive results during breast MRI screening may have adverse psychological effects. Methods Impact of Event Scale measurements in 103 high-risk women enrolled in a longitudinal MRI screening study and comparison of subjects with normal results vs. those with prior recall events. Results Of 189 MRI scans performed, 64 (34%) prompted further evaluation. Subjects with previously abnormal results had significantly higher Avoidance scores at the time of their second MRI. Multivariate analysis showed this was driven by the greater number of BRCA1/2 carriers in that group but was not related to screening recall. Conclusions Practitioners' concerns about the high false positive rate of breast MRI may not be matched by actual psychological effects in most high-risk women.

Original language	English (US)
Pages (from-to)	365-371
Number of pages	7
Journal	Breast Cancer Research and Treatment
Volume	115
Issue number	2
DOIs	https://doi.org/10.1007/s10549-008-0140-0
State	Published - May 2009

Keywords

BRCA1 genes
BRCA2 genes
Breast neoplasms/genetics
Magnetic resonance imaging/adverse effects
Psychological stress
Sensitivity and specificity

ASJC Scopus subject areas

Oncology
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1007/s10549-008-0140-0

Cite this

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title = "Psychological impact of recall in high-risk breast MRI screening",

abstract = "Purpose To address the widespread concern that false-positive results during breast MRI screening may have adverse psychological effects. Methods Impact of Event Scale measurements in 103 high-risk women enrolled in a longitudinal MRI screening study and comparison of subjects with normal results vs. those with prior recall events. Results Of 189 MRI scans performed, 64 (34%) prompted further evaluation. Subjects with previously abnormal results had significantly higher Avoidance scores at the time of their second MRI. Multivariate analysis showed this was driven by the greater number of BRCA1/2 carriers in that group but was not related to screening recall. Conclusions Practitioners' concerns about the high false positive rate of breast MRI may not be matched by actual psychological effects in most high-risk women.",

keywords = "BRCA1 genes, BRCA2 genes, Breast neoplasms/genetics, Magnetic resonance imaging/adverse effects, Psychological stress, Sensitivity and specificity",

author = "O'Neill, {Suzanne M.} and Rubinstein, {Wendy S.} and Sener, {Stephen F.} and Weissman, {Scott M.} and Newlin, {Anna C.} and West, {Daniel K.} and Ecanow, {David B.} and Rademaker, {Alfred W.} and Edelman, {Robert R.}",

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T1 - Psychological impact of recall in high-risk breast MRI screening

AU - O'Neill, Suzanne M.

AU - Rubinstein, Wendy S.

AU - Sener, Stephen F.

AU - Weissman, Scott M.

AU - Newlin, Anna C.

AU - West, Daniel K.

AU - Ecanow, David B.

AU - Rademaker, Alfred W.

AU - Edelman, Robert R.

PY - 2009/5

Y1 - 2009/5

N2 - Purpose To address the widespread concern that false-positive results during breast MRI screening may have adverse psychological effects. Methods Impact of Event Scale measurements in 103 high-risk women enrolled in a longitudinal MRI screening study and comparison of subjects with normal results vs. those with prior recall events. Results Of 189 MRI scans performed, 64 (34%) prompted further evaluation. Subjects with previously abnormal results had significantly higher Avoidance scores at the time of their second MRI. Multivariate analysis showed this was driven by the greater number of BRCA1/2 carriers in that group but was not related to screening recall. Conclusions Practitioners' concerns about the high false positive rate of breast MRI may not be matched by actual psychological effects in most high-risk women.

AB - Purpose To address the widespread concern that false-positive results during breast MRI screening may have adverse psychological effects. Methods Impact of Event Scale measurements in 103 high-risk women enrolled in a longitudinal MRI screening study and comparison of subjects with normal results vs. those with prior recall events. Results Of 189 MRI scans performed, 64 (34%) prompted further evaluation. Subjects with previously abnormal results had significantly higher Avoidance scores at the time of their second MRI. Multivariate analysis showed this was driven by the greater number of BRCA1/2 carriers in that group but was not related to screening recall. Conclusions Practitioners' concerns about the high false positive rate of breast MRI may not be matched by actual psychological effects in most high-risk women.

KW - BRCA1 genes

KW - BRCA2 genes

KW - Breast neoplasms/genetics

KW - Magnetic resonance imaging/adverse effects

KW - Psychological stress

KW - Sensitivity and specificity

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Psychological impact of recall in high-risk breast MRI screening

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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