To the Editor: Goldman et al. (Feb. 18 issue)1 report new and important information about psychosis and water metabolism. The focus of their paper was on altered thirst and osmotic regulation. In a previous study, these investigators demonstrated a correlation between changes in serum sodium levels and changes in body weight (r = -0.74) among patients with chronic psychosis who were subject to water intoxication.2 We (r = -0.95),3 Koczapski et al. (r = -0.89),4 and Delva and Crammer (r between -0.65 and -0.99)5 have also found strong correlations between changes in serum sodium levels and body weight. However, the.
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