Psychosocial Considerations in Pubertal Suppression Treatment

Diane Chen, Jennifer M. Birnkrant, Marco A. Hidalgo

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


Pubertal suppression with gonadotropin-releasing hormone analogues (GnRHa) is considered a reversible treatment that has been associated with improved psychosocial outcomes among transgender and gender-nonconforming youth. However, there has been debate regarding whether GnRHa is truly reversible, with some arguing that certain psychosocial risks or “side effects” warrant consideration. The goal of this chapter is to highlight these psychosocial considerations, including (1) controversy surrounding the possible effects of GnRHa on gender identity and/or sexuality development, (2) unknown neurocognitive sequelae of GnRHa, (3) psychosocial implications of medical side effects (e.g., fertility, sexual functioning), and (4) family factors related to GnRHa.

Original languageEnglish (US)
Title of host publicationPubertal Suppression in Transgender Youth
Number of pages7
ISBN (Electronic)9780323569637
StatePublished - Jan 1 2018


  • Family stressors
  • Fertility
  • Gender identity development
  • Neurocognitive effects
  • Psychosocial considerations
  • Pubertal suppression
  • Sexual function

ASJC Scopus subject areas

  • General Medicine


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