Psychosocial Factors Associated with Subclinical Atherosclerosis in South Asians: The MASALA Study

Bijal M. Shah*, Shriraj Shah, Namratha R. Kandula, Meghana D. Gadgil, Alka M. Kanaya

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

21 Scopus citations


South Asians have the highest rates of premature atherosclerotic cardiovascular disease amongst all ethnic groups in the world; however this risk cannot be fully explained by traditional risk factors. Participants from the Mediators of Atherosclerosis in South Asians Living in America Study were included in this cross-sectional analysis. The purpose of this study was to investigate the association of psychosocial factors (including anger, anxiety, depressive symptoms, current and chronic stress, and everyday hassles) with carotid intima-media thickness (CIMT). Three multivariate models were examined to evaluate the association between the psychosocial factors and CIMT. Findings suggest that the impact of psychosocial factors on subclinical atherosclerosis is differential for South Asian men and women. For men, anxiety and depression were associated; while for women, stress was associated with common carotid intima media thickness, independent of traditional CVD risk factors, diet and physical activity.

Original languageEnglish (US)
Pages (from-to)1317-1327
Number of pages11
JournalJournal of Immigrant and Minority Health
Issue number6
StatePublished - Dec 1 2016


  • Atherosclerosis
  • MASALA Study
  • Risk factors
  • South Asians

ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health
  • Epidemiology


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