Pulmonary Cryptococcosis Complicating Severe Coronavirus Infectious Disease 2019: A Case Report and Review of the Literature

Rebecca Osborn; Michael Angarone; Kendall David Kling; Claudia A Hawkins

doi:10.1097/IPC.0000000000001191

Pulmonary Cryptococcosis Complicating Severe Coronavirus Infectious Disease 2019: A Case Report and Review of the Literature

Rebecca Osborn^*, Michael Angarone, Kendall David Kling, Claudia A Hawkins

^*Corresponding author for this work

Medicine, Infectious Diseases Division

Research output: Contribution to journal › Article › peer-review

Abstract

Many case reports have detailed fungal infections associated with coronavirus infectious disease-2019 (COVID-19); however, few reports have described cryptococcal infection in individuals with COVID-19. The use of immunomodulatory medications as part of COVID-19 treatment including corticosteroids and tocilizumab increases the risk of invasive fungal infections. Herein we review the existing reports of cryptococcal infection in the setting of COVID-19 and present a case of a previously immunocompetent patient who was diagnosed with pulmonary cryptococcosis after being treated with prolonged corticosteroids for severe COVID-19 and organizing pneumonia.

Original language	English (US)
Article number	e1191
Journal	Infectious Diseases in Clinical Practice
Volume	31
Issue number	1
DOIs	https://doi.org/10.1097/IPC.0000000000001191
State	Published - Jan 1 2023

Keywords

COVID-19
Cryptococcus
fungal pneumonia

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1097/IPC.0000000000001191

Cite this

@article{217e6038f5f840babba2b19b9617d2cc,

title = "Pulmonary Cryptococcosis Complicating Severe Coronavirus Infectious Disease 2019: A Case Report and Review of the Literature",

abstract = "Many case reports have detailed fungal infections associated with coronavirus infectious disease-2019 (COVID-19); however, few reports have described cryptococcal infection in individuals with COVID-19. The use of immunomodulatory medications as part of COVID-19 treatment including corticosteroids and tocilizumab increases the risk of invasive fungal infections. Herein we review the existing reports of cryptococcal infection in the setting of COVID-19 and present a case of a previously immunocompetent patient who was diagnosed with pulmonary cryptococcosis after being treated with prolonged corticosteroids for severe COVID-19 and organizing pneumonia.",

keywords = "COVID-19, Cryptococcus, fungal pneumonia",

author = "Rebecca Osborn and Michael Angarone and Kling, \{Kendall David\} and Hawkins, \{Claudia A\}",

year = "2023",

month = jan,

day = "1",

doi = "10.1097/IPC.0000000000001191",

language = "English (US)",

volume = "31",

journal = "Infectious Diseases in Clinical Practice",

issn = "1056-9103",

publisher = "Lippincott Williams and Wilkins Ltd.",

number = "1",

}

TY - JOUR

T1 - Pulmonary Cryptococcosis Complicating Severe Coronavirus Infectious Disease 2019

T2 - A Case Report and Review of the Literature

AU - Osborn, Rebecca

AU - Angarone, Michael

AU - Kling, Kendall David

AU - Hawkins, Claudia A

PY - 2023/1/1

Y1 - 2023/1/1

N2 - Many case reports have detailed fungal infections associated with coronavirus infectious disease-2019 (COVID-19); however, few reports have described cryptococcal infection in individuals with COVID-19. The use of immunomodulatory medications as part of COVID-19 treatment including corticosteroids and tocilizumab increases the risk of invasive fungal infections. Herein we review the existing reports of cryptococcal infection in the setting of COVID-19 and present a case of a previously immunocompetent patient who was diagnosed with pulmonary cryptococcosis after being treated with prolonged corticosteroids for severe COVID-19 and organizing pneumonia.

AB - Many case reports have detailed fungal infections associated with coronavirus infectious disease-2019 (COVID-19); however, few reports have described cryptococcal infection in individuals with COVID-19. The use of immunomodulatory medications as part of COVID-19 treatment including corticosteroids and tocilizumab increases the risk of invasive fungal infections. Herein we review the existing reports of cryptococcal infection in the setting of COVID-19 and present a case of a previously immunocompetent patient who was diagnosed with pulmonary cryptococcosis after being treated with prolonged corticosteroids for severe COVID-19 and organizing pneumonia.

KW - COVID-19

KW - Cryptococcus

KW - fungal pneumonia

UR - http://www.scopus.com/inward/record.url?scp=85207666071&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85207666071&partnerID=8YFLogxK

U2 - 10.1097/IPC.0000000000001191

DO - 10.1097/IPC.0000000000001191

M3 - Article

AN - SCOPUS:85207666071

SN - 1056-9103

VL - 31

JO - Infectious Diseases in Clinical Practice

JF - Infectious Diseases in Clinical Practice

IS - 1

M1 - e1191

ER -

Pulmonary Cryptococcosis Complicating Severe Coronavirus Infectious Disease 2019: A Case Report and Review of the Literature

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this