Pulmonary growth abnormalities as etiologies for pediatric pulmonary hypertension

George B. Mallory*, David R. Spielberg, Manuel Silva-Carmona

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations


Pulmonary growth abnormality (PGA) is a common type of diffuse lung disease in infants. Although the histologic and radiographic features of PGA have been described in the literature in varying detail, the clinical spectrum of disease has not. The array of case series and case reports has led to a clinical picture that could be confusing to clinicians. We describe three subsets of PGA, including its association with the histologic marker of pulmonary interstitial glycogenosis, and its common association with pulmonary hypertension. We propose a new approach to what we consider an increasingly broad array of different disease entities.

Original languageEnglish (US)
Pages (from-to)678-685
Number of pages8
JournalPediatric Pulmonology
Issue number3
StatePublished - Mar 2021
Externally publishedYes


  • filamin A mutation
  • pulmonary growth abnormality
  • pulmonary hypertension
  • pulmonary hypoplasia
  • pulmonary interstitial glycogenosis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Pulmonary and Respiratory Medicine


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