Pumping Up the Synapse

Peter Penzes*

*Corresponding author for this work

Research output: Contribution to journalShort surveypeer-review

4 Scopus citations

Abstract

Synchronized control of excitatory and inhibitory synapse maturation is crucial for normal brain wiring, while its dysfunction leads to neurodevelopmental disorders, including autism. A paper in this issue of Neuron identified a novel role for the KCC2 pump, also responsible for the GABAergic synapse developmental switch, in regulating spiny excitatory synapse maturation, implicating it in the coordinated maturation of inhibitory and excitatory synapses.

Original languageEnglish (US)
Pages (from-to)942-944
Number of pages3
JournalNeuron
Volume56
Issue number6
DOIs
StatePublished - Dec 20 2007

ASJC Scopus subject areas

  • Neuroscience(all)

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