Pure seminoma

Bharat B Mittal*, R. Oyasu, W. N. Brand

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations

Abstract

We reviewed 40 patients with pure seminoma, paying particular attention to extratesticular and anaplastic seminomas, which have poor prognoses. In our study, two of the three patients with extratesticular seminoma had anaplastic histology, this association has not been stressed previously. We recommend that extratesticular seminoma, particularly with anaplastic histology, be considered for regional radiotherapy combined with chemotherapy. Bone scan should be part of the initial work-up of patients with extratesticular seminoma. Our review showed a low incidence of lymphatic and/or vascular invasion in typical as well as anaplastic seminoma. This could be because we did not interpret floating tumor cells in a vessel as indicative of vessel invasion. Finally, we investigated the significance of syncytiotrophoblastic giant cells in pure seminoma and found that they do not worsen prognosis.

Original languageEnglish (US)
Pages (from-to)649-651
Number of pages3
JournalInternational Journal of Radiation Oncology, Biology, Physics
Volume7
Issue number5
DOIs
StatePublished - Jan 1 1981

Keywords

  • Anaplastic seminoma
  • Extratesticular seminoma
  • Pure seminoma

ASJC Scopus subject areas

  • Radiation
  • Oncology
  • Radiology Nuclear Medicine and imaging
  • Cancer Research

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