Pure seminoma

Bharat B Mittal; R. Oyasu; W. N. Brand

doi:10.1016/0360-3016(81)90380-1

Pure seminoma

Bharat B Mittal^*, R. Oyasu, W. N. Brand

^*Corresponding author for this work

Radiation Oncology

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

We reviewed 40 patients with pure seminoma, paying particular attention to extratesticular and anaplastic seminomas, which have poor prognoses. In our study, two of the three patients with extratesticular seminoma had anaplastic histology, this association has not been stressed previously. We recommend that extratesticular seminoma, particularly with anaplastic histology, be considered for regional radiotherapy combined with chemotherapy. Bone scan should be part of the initial work-up of patients with extratesticular seminoma. Our review showed a low incidence of lymphatic and/or vascular invasion in typical as well as anaplastic seminoma. This could be because we did not interpret floating tumor cells in a vessel as indicative of vessel invasion. Finally, we investigated the significance of syncytiotrophoblastic giant cells in pure seminoma and found that they do not worsen prognosis.

Original language	English (US)
Pages (from-to)	649-651
Number of pages	3
Journal	International Journal of Radiation Oncology, Biology, Physics
Volume	7
Issue number	5
DOIs	https://doi.org/10.1016/0360-3016(81)90380-1
State	Published - Jan 1 1981

Keywords

Anaplastic seminoma
Extratesticular seminoma
Pure seminoma

ASJC Scopus subject areas

Radiation
Oncology
Radiology Nuclear Medicine and imaging
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/0360-3016(81)90380-1

Cite this

@article{b6e2516514b047a19b5cd3085680dddd,

title = "Pure seminoma",

abstract = "We reviewed 40 patients with pure seminoma, paying particular attention to extratesticular and anaplastic seminomas, which have poor prognoses. In our study, two of the three patients with extratesticular seminoma had anaplastic histology, this association has not been stressed previously. We recommend that extratesticular seminoma, particularly with anaplastic histology, be considered for regional radiotherapy combined with chemotherapy. Bone scan should be part of the initial work-up of patients with extratesticular seminoma. Our review showed a low incidence of lymphatic and/or vascular invasion in typical as well as anaplastic seminoma. This could be because we did not interpret floating tumor cells in a vessel as indicative of vessel invasion. Finally, we investigated the significance of syncytiotrophoblastic giant cells in pure seminoma and found that they do not worsen prognosis.",

keywords = "Anaplastic seminoma, Extratesticular seminoma, Pure seminoma",

author = "Mittal, {Bharat B} and R. Oyasu and Brand, {W. N.}",

year = "1981",

month = jan,

day = "1",

doi = "10.1016/0360-3016(81)90380-1",

language = "English (US)",

volume = "7",

pages = "649--651",

journal = "International Journal of Radiation Oncology Biology Physics",

issn = "0360-3016",

publisher = "Elsevier Inc.",

number = "5",

}

TY - JOUR

T1 - Pure seminoma

AU - Mittal, Bharat B

AU - Oyasu, R.

AU - Brand, W. N.

PY - 1981/1/1

Y1 - 1981/1/1

N2 - We reviewed 40 patients with pure seminoma, paying particular attention to extratesticular and anaplastic seminomas, which have poor prognoses. In our study, two of the three patients with extratesticular seminoma had anaplastic histology, this association has not been stressed previously. We recommend that extratesticular seminoma, particularly with anaplastic histology, be considered for regional radiotherapy combined with chemotherapy. Bone scan should be part of the initial work-up of patients with extratesticular seminoma. Our review showed a low incidence of lymphatic and/or vascular invasion in typical as well as anaplastic seminoma. This could be because we did not interpret floating tumor cells in a vessel as indicative of vessel invasion. Finally, we investigated the significance of syncytiotrophoblastic giant cells in pure seminoma and found that they do not worsen prognosis.

AB - We reviewed 40 patients with pure seminoma, paying particular attention to extratesticular and anaplastic seminomas, which have poor prognoses. In our study, two of the three patients with extratesticular seminoma had anaplastic histology, this association has not been stressed previously. We recommend that extratesticular seminoma, particularly with anaplastic histology, be considered for regional radiotherapy combined with chemotherapy. Bone scan should be part of the initial work-up of patients with extratesticular seminoma. Our review showed a low incidence of lymphatic and/or vascular invasion in typical as well as anaplastic seminoma. This could be because we did not interpret floating tumor cells in a vessel as indicative of vessel invasion. Finally, we investigated the significance of syncytiotrophoblastic giant cells in pure seminoma and found that they do not worsen prognosis.

KW - Anaplastic seminoma

KW - Extratesticular seminoma

KW - Pure seminoma

UR - http://www.scopus.com/inward/record.url?scp=0019450046&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0019450046&partnerID=8YFLogxK

U2 - 10.1016/0360-3016(81)90380-1

DO - 10.1016/0360-3016(81)90380-1

M3 - Article

C2 - 7275729

AN - SCOPUS:0019450046

SN - 0360-3016

VL - 7

SP - 649

EP - 651

JO - International Journal of Radiation Oncology Biology Physics

JF - International Journal of Radiation Oncology Biology Physics

IS - 5

ER -

Pure seminoma

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this