TY - JOUR
T1 - Quality of Life Considerations in Gynecologic Cancer
AU - PENSON, Richard T.
AU - WENZEL, Lari B.
AU - VERGOTE, Ignace
AU - CELLA, David
PY - 2006/11
Y1 - 2006/11
N2 - Quality of life (QOL) is a fundamental consideration for patients with life threatening diseases. Major evolving paradigms are discussed: improved QOL with laparoscopic surgery, the impact on QOL of intraperitoneal chemotherapy for optimally cytoreduced ovarian cancer, combination therapy, sexuality, and survivorship. The goals of treatment for many patients with gynecologic tumors remain largely palliative, and patient reported QOL is the primary outcome determining the utility of treatment. Particularly in this area, QOL endpoints are increasingly important in clinical trials. The QOL issues facing gynecologic cancer patients, the use of validated QOL instruments, recent advances in the evaluation of interventions, and changes in concepts related to QOL are reviewed.
AB - Quality of life (QOL) is a fundamental consideration for patients with life threatening diseases. Major evolving paradigms are discussed: improved QOL with laparoscopic surgery, the impact on QOL of intraperitoneal chemotherapy for optimally cytoreduced ovarian cancer, combination therapy, sexuality, and survivorship. The goals of treatment for many patients with gynecologic tumors remain largely palliative, and patient reported QOL is the primary outcome determining the utility of treatment. Particularly in this area, QOL endpoints are increasingly important in clinical trials. The QOL issues facing gynecologic cancer patients, the use of validated QOL instruments, recent advances in the evaluation of interventions, and changes in concepts related to QOL are reviewed.
UR - http://www.scopus.com/inward/record.url?scp=33845257555&partnerID=8YFLogxK
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U2 - 10.1016/S0020-7292(06)60040-4
DO - 10.1016/S0020-7292(06)60040-4
M3 - Article
C2 - 17161164
AN - SCOPUS:33845257555
SN - 0020-7292
VL - 95
SP - S247-S257
JO - International Journal of Gynecology and Obstetrics
JF - International Journal of Gynecology and Obstetrics
IS - SUPPL. 1
ER -
