TY - JOUR
T1 - Quality of life considerations in patients with advanced lung cancer
AU - Cella, David
PY - 2004/12
Y1 - 2004/12
N2 - Quality of life (QOL) is an important consideration in the treatment of patients with advanced lung cancer because treatment is largely palliative. Moreover, QOL predicts survival in non-small cell lung cancer, and there is increasing acceptance by clinicians and regulatory authorities of symptoms and QOL as primary or coprimary endpoints in clinical trials. This article reviews the signs and symptoms of advanced lung cancer that commonly affect QOL, and the prevalence, emergence, and decline of symptoms in patients with good performance status during and after treatment. Next, it details the various tools for measuring QOL in patients with lung cancer and data that support the use of QOL data to guide individual treatment decisions. Finally, it discusses the need for a better understanding of the QOL and treatment preferences of patients with poor performance status.
AB - Quality of life (QOL) is an important consideration in the treatment of patients with advanced lung cancer because treatment is largely palliative. Moreover, QOL predicts survival in non-small cell lung cancer, and there is increasing acceptance by clinicians and regulatory authorities of symptoms and QOL as primary or coprimary endpoints in clinical trials. This article reviews the signs and symptoms of advanced lung cancer that commonly affect QOL, and the prevalence, emergence, and decline of symptoms in patients with good performance status during and after treatment. Next, it details the various tools for measuring QOL in patients with lung cancer and data that support the use of QOL data to guide individual treatment decisions. Finally, it discusses the need for a better understanding of the QOL and treatment preferences of patients with poor performance status.
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U2 - 10.1053/j.seminoncol.2004.10.004
DO - 10.1053/j.seminoncol.2004.10.004
M3 - Article
C2 - 15599830
AN - SCOPUS:10044279481
SN - 0093-7754
VL - 31
SP - 16
EP - 20
JO - Seminars in Oncology
JF - Seminars in Oncology
IS - SUPPL. 11
ER -