Abstract
Background: This study assessed quality of life (QOL) in adult survivors of pediatric heart transplantation who survived ≥ 10 years after transplantation. Methods: Prospective data were collected from heart transplant recipients who were aged ≥ 18 years and had survived ≥ 10 years after transplantation (transplantation between July 3, 1986, and April 4, 1997). QOL data were collected from patients using the Medical Outcomes Study 36-Item Short Form (SF-36) Health Survey. Clinical data were collected from medical records. Statistical analyses included frequencies and measures of central tendency. Results: Twenty-three patients (65% men, 91% white) completed the study. At the study initiation, they were a mean age of 9.0 ± 7.1 years at transplantation, and were a mean age of 25.2 ± 5.5 years (range, 18-34 years) and a mean of 16.2 ± 3.0 years (range, 11-22 years) post-transplantation. Most were in school or working. Mean patient QOL scores from the SF-36v2 survey were 50.56 ± 0.5 (range, 27.3-68.9) for physical health and 49.88 ± 11.72 (range, 23.56-62.84) for mental health, similar to the general United States population. Late complications were frequent, including transplant coronary artery disease, 3; repeat heart transplantation, 2; post-transplantation lymphoproliferative disorder, 6; kidney transplantation, 5; acute late rejection, 5; and arrhythmias, 4. Conclusion: This report of QOL in adult survivors of pediatric heart transplantation shows patient perception of physical and mental health is similar to the general population despite serious late complications. A multicenter study is planned to further evaluate QOL in this unique cohort.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 661-666 |
| Number of pages | 6 |
| Journal | Journal of Heart and Lung Transplantation |
| Volume | 28 |
| Issue number | 7 |
| DOIs | |
| State | Published - Jul 1 2009 |
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ASJC Scopus subject areas
- Surgery
- Pulmonary and Respiratory Medicine
- Cardiology and Cardiovascular Medicine
- Transplantation
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Quality of Life in Adult Survivors Greater Than 10 Years After Pediatric Heart Transplantation. / Petroski, Rebecca A.; Grady, Kathleen L; Rodgers, Sherrie; Backer, Carl L; Kulikowska, Agnieszka; Canter, Charles; Pahl, Elfriede.
In: Journal of Heart and Lung Transplantation, Vol. 28, No. 7, 01.07.2009, p. 661-666.Research output: Contribution to journal › Article
TY - JOUR
T1 - Quality of Life in Adult Survivors Greater Than 10 Years After Pediatric Heart Transplantation
AU - Petroski, Rebecca A.
AU - Grady, Kathleen L
AU - Rodgers, Sherrie
AU - Backer, Carl L
AU - Kulikowska, Agnieszka
AU - Canter, Charles
AU - Pahl, Elfriede
PY - 2009/7/1
Y1 - 2009/7/1
N2 - Background: This study assessed quality of life (QOL) in adult survivors of pediatric heart transplantation who survived ≥ 10 years after transplantation. Methods: Prospective data were collected from heart transplant recipients who were aged ≥ 18 years and had survived ≥ 10 years after transplantation (transplantation between July 3, 1986, and April 4, 1997). QOL data were collected from patients using the Medical Outcomes Study 36-Item Short Form (SF-36) Health Survey. Clinical data were collected from medical records. Statistical analyses included frequencies and measures of central tendency. Results: Twenty-three patients (65% men, 91% white) completed the study. At the study initiation, they were a mean age of 9.0 ± 7.1 years at transplantation, and were a mean age of 25.2 ± 5.5 years (range, 18-34 years) and a mean of 16.2 ± 3.0 years (range, 11-22 years) post-transplantation. Most were in school or working. Mean patient QOL scores from the SF-36v2 survey were 50.56 ± 0.5 (range, 27.3-68.9) for physical health and 49.88 ± 11.72 (range, 23.56-62.84) for mental health, similar to the general United States population. Late complications were frequent, including transplant coronary artery disease, 3; repeat heart transplantation, 2; post-transplantation lymphoproliferative disorder, 6; kidney transplantation, 5; acute late rejection, 5; and arrhythmias, 4. Conclusion: This report of QOL in adult survivors of pediatric heart transplantation shows patient perception of physical and mental health is similar to the general population despite serious late complications. A multicenter study is planned to further evaluate QOL in this unique cohort.
AB - Background: This study assessed quality of life (QOL) in adult survivors of pediatric heart transplantation who survived ≥ 10 years after transplantation. Methods: Prospective data were collected from heart transplant recipients who were aged ≥ 18 years and had survived ≥ 10 years after transplantation (transplantation between July 3, 1986, and April 4, 1997). QOL data were collected from patients using the Medical Outcomes Study 36-Item Short Form (SF-36) Health Survey. Clinical data were collected from medical records. Statistical analyses included frequencies and measures of central tendency. Results: Twenty-three patients (65% men, 91% white) completed the study. At the study initiation, they were a mean age of 9.0 ± 7.1 years at transplantation, and were a mean age of 25.2 ± 5.5 years (range, 18-34 years) and a mean of 16.2 ± 3.0 years (range, 11-22 years) post-transplantation. Most were in school or working. Mean patient QOL scores from the SF-36v2 survey were 50.56 ± 0.5 (range, 27.3-68.9) for physical health and 49.88 ± 11.72 (range, 23.56-62.84) for mental health, similar to the general United States population. Late complications were frequent, including transplant coronary artery disease, 3; repeat heart transplantation, 2; post-transplantation lymphoproliferative disorder, 6; kidney transplantation, 5; acute late rejection, 5; and arrhythmias, 4. Conclusion: This report of QOL in adult survivors of pediatric heart transplantation shows patient perception of physical and mental health is similar to the general population despite serious late complications. A multicenter study is planned to further evaluate QOL in this unique cohort.
UR - http://www.scopus.com/inward/record.url?scp=67649094103&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=67649094103&partnerID=8YFLogxK
U2 - 10.1016/j.healun.2009.04.004
DO - 10.1016/j.healun.2009.04.004
M3 - Article
C2 - 19560692
AN - SCOPUS:67649094103
VL - 28
SP - 661
EP - 666
JO - Journal of Heart and Lung Transplantation
JF - Journal of Heart and Lung Transplantation
SN - 1053-2498
IS - 7
ER -