Quantification of arsenic, lead, mercury and cadmium in newborn dried blood spots

William E. Funk; John K. McGee; Andrew F. Olshan; Andrew J. Ghio

doi:10.3109/1354750X.2012.750379

Quantification of arsenic, lead, mercury and cadmium in newborn dried blood spots

William E. Funk^*, John K. McGee, Andrew F. Olshan, Andrew J. Ghio

^*Corresponding author for this work

Preventive Medicine

Research output: Contribution to journal › Article › peer-review

46 Scopus citations

Abstract

Exposures to heavy metals during fetal and perinatal development are of particular concern. Yet, the health impacts of exposures to toxic metals during these early stages of human development are not well understood due to the paucity of in vivo human data. Dried blood spots (DBS), collected by public health departments to screen for inherited metabolic errors and other disorders, are routinely archived and can be used for exposure assessment. Here we report an improved method for quantifying arsenic, lead, mercury and cadmium in newborn DBS to facilitate epidemiologic research on the health effects of early exposures to toxic metals.

Original language	English (US)
Pages (from-to)	174-177
Number of pages	4
Journal	Biomarkers
Volume	18
Issue number	2
DOIs	https://doi.org/10.3109/1354750X.2012.750379
State	Published - Mar 2013

Funding

The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this article. This research was supported in part by a grant from the National Institute of Environmental Health Sciences (P30ES010126).

Keywords

Arsenic
Cadmium
Dried blood spots
Epidemiology
Lead
Mercury
Neonatal

ASJC Scopus subject areas

Biochemistry
Clinical Biochemistry
Health, Toxicology and Mutagenesis

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.3109/1354750X.2012.750379

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title = "Quantification of arsenic, lead, mercury and cadmium in newborn dried blood spots",

abstract = "Exposures to heavy metals during fetal and perinatal development are of particular concern. Yet, the health impacts of exposures to toxic metals during these early stages of human development are not well understood due to the paucity of in vivo human data. Dried blood spots (DBS), collected by public health departments to screen for inherited metabolic errors and other disorders, are routinely archived and can be used for exposure assessment. Here we report an improved method for quantifying arsenic, lead, mercury and cadmium in newborn DBS to facilitate epidemiologic research on the health effects of early exposures to toxic metals.",

keywords = "Arsenic, Cadmium, Dried blood spots, Epidemiology, Lead, Mercury, Neonatal",

author = "Funk, {William E.} and McGee, {John K.} and Olshan, {Andrew F.} and Ghio, {Andrew J.}",

note = "Funding Information: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this article. This research was supported in part by a grant from the National Institute of Environmental Health Sciences (P30ES010126).",

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doi = "10.3109/1354750X.2012.750379",

language = "English (US)",

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AU - Funk, William E.

AU - McGee, John K.

AU - Olshan, Andrew F.

AU - Ghio, Andrew J.

N1 - Funding Information: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this article. This research was supported in part by a grant from the National Institute of Environmental Health Sciences (P30ES010126).

PY - 2013/3

Y1 - 2013/3

N2 - Exposures to heavy metals during fetal and perinatal development are of particular concern. Yet, the health impacts of exposures to toxic metals during these early stages of human development are not well understood due to the paucity of in vivo human data. Dried blood spots (DBS), collected by public health departments to screen for inherited metabolic errors and other disorders, are routinely archived and can be used for exposure assessment. Here we report an improved method for quantifying arsenic, lead, mercury and cadmium in newborn DBS to facilitate epidemiologic research on the health effects of early exposures to toxic metals.

AB - Exposures to heavy metals during fetal and perinatal development are of particular concern. Yet, the health impacts of exposures to toxic metals during these early stages of human development are not well understood due to the paucity of in vivo human data. Dried blood spots (DBS), collected by public health departments to screen for inherited metabolic errors and other disorders, are routinely archived and can be used for exposure assessment. Here we report an improved method for quantifying arsenic, lead, mercury and cadmium in newborn DBS to facilitate epidemiologic research on the health effects of early exposures to toxic metals.

KW - Arsenic

KW - Cadmium

KW - Dried blood spots

KW - Epidemiology

KW - Lead

KW - Mercury

KW - Neonatal

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Quantification of arsenic, lead, mercury and cadmium in newborn dried blood spots

Abstract

Funding

Keywords

ASJC Scopus subject areas

UN SDGs

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