Quantitative analysis of left atrial function during left ventricular ischemia with and without left atrial ischemia: A real-time 3-dimensional echocardiographic study

Fabrice Bauer, Michael Jones, Xin Qin Jian, Peter Castro, Junko Asada, Marta Sitges, Lisa A. Cardon, Hiroyuki Tsujino, Arthur D. Zetts, Julio A. Panza, James D. Thomas, Takahiro Shiota*

*Corresponding author for this work

Research output: Contribution to journalArticle

16 Scopus citations

Abstract

Left atrial (LA) systolic and diastolic function were analyzed in an animal model of acute left ventricular ischemia with LA ischemia by proximal left circumflex coronary artery occlusion or without LA ischemia by midleft anterior descending coronary artery occlusion (7 sheep in each group). LA pressures and LA volumes were simultaneously recorded using a catheter and real-time 3-dimensional echocardiography, respectively. LA stroke volume represented 63% of left ventricular stroke volume during left anterior descending coronary artery occlusion, but only 32% during left circumflex coronary artery occlusion. This animal study with 3-dimensional echocardiographic determination of absolute LA volumes demonstrated dramatic depression of LA function during proximal left circumflex coronary artery occlusion as compared with left anterior descending coronary artery occlusion.

Original languageEnglish (US)
Pages (from-to)795-801
Number of pages7
JournalJournal of the American Society of Echocardiography
Volume18
Issue number8
DOIs
StatePublished - Aug 1 2005

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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