Quantitative assessment of in-stent dimensions: A comparison of 64 and 16 detector multislice computed tomography to intravascular ultrasound

Nirat Beohar, Joel D. Robbins, Brendan J. Cavanaugh, Asimul H. Ansari, Vahid Yaghmai, James Carr, Charles J. Davidson*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

14 Scopus citations

Abstract

Objectives: To determine the utility of multislice computed tomography (MSCT) technology to evaluate coronary stent luminal diameter. Background: Stent metal induced "blooming" artifact makes quantitative coronary angiography by MSCT difficult. There is a paucity of data on the efficacy of using 64 and 16 detector MSCT in evaluating coronary stents. Methods: We evaluated four commercially available bare metal and polymer coated drug eluting stents using 64 and 16 detector MSCT for the following: (1) Strut density in Hounsfield's Units (Hu) using a 2 mm MIP; (2) In-stent luminal diameter (ISLD) measured by MSCT compared to intravascular ultrasound (IVUS). Results: Increased strut thickness did not correlate with greater strut density as measured in Hu (R2 = 0.05, P = 0.29). The ISLD by 16 MSCT vs. IVUS is: Vision 1.63 ± 0.58 mm vs. 2.8 ± 0.0; Cypher 1.80 ± 0.00 vs. 2.9 ± 0.0; Taxus 1.87 ± 0.58 vs. 2.9 ± 0.0; Liberté 1.80 ± 0.10 vs. 3.0 ± 0.1 (P < 0.01). ISLD determined by 64 MSCT vs. IVUS is: Vision 1.73 ± 0.06 mm vs. 2.8 ± 0.0; Cypher 1.87 ± 0.12 vs. 2.9 ± 0.0; Taxus 1.77 ± 0.06 vs. 2.9 ± 0.0; Liberté 1.80 ± 0.10 vs. 3.0 ± 0.1 (P < 0.01). Conclusions: When compared to IVUS measurements, MSCT results in a significant, underestimation of ISLD. This consistent underestimation (even with 64 MSCT) limits the applicability of CT angiography to quantify in-stent restenosis.

Original languageEnglish (US)
Pages (from-to)8-10
Number of pages3
JournalCatheterization and Cardiovascular Interventions
Volume68
Issue number1
DOIs
StatePublished - Jul 2006

Keywords

  • Coronary stent
  • Imaging
  • Tomography

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging

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