Quantitative assessment of mitral regurgitation: Validation of new methods

Paaladinesh Thavendiranathan, Dermot Phelan, James D. Thomas, Scott D. Flamm, Thomas H. Marwick*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

72 Scopus citations


Accurate assessment of mitral regurgitation (MR) severity is important for clinical decision making, prognostication, and decisions regarding timing of surgical intervention. The most common method for noninvasive assessment of MR has been with 2-dimensional transthoracic echocardiography, which is often used as a qualitative tool. Several newer noninvasive modalities including 3-dimensional echocardiography, cardiac magnetic resonance imaging, and cardiac computed tomography have also become available for this purpose; however, their role in routine clinical practice is not clearly defined. In this review, we provide an overview of these newer modalities for quantitative assessment of MR severity.

Original languageEnglish (US)
Pages (from-to)1470-1483
Number of pages14
JournalJournal of the American College of Cardiology
Issue number16
StatePublished - Oct 16 2012


  • 3D-echocardiography
  • cardiac computed tomography
  • cardiac magnetic resonance imaging
  • mitral regurgitation
  • quantification

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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