Quantitative imaging and microanalysis with a scanning soft x-ray microscope

C. Jacobsen*, J. M. Kenney, J. Kirz, R. J. Rosser, F. Cinotti, H. Rarback, J. Pine

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


A scanning soft X-ray microscope has been developed that uses synchrotron radiation focused by a Fresnel zone plate to form a submicron beamspot on the specimen. Transmitted X-rays are detected and used to form a quantitative map of specimen absorptivity. Applications of the instrument to the imaging of whole wet cells and to the mapping of calcium in sections of bone are presented, with a resolution of 300 nm and an elemental sensitivity of 2 mu g cm-2.

Original languageEnglish (US)
Article number002
Pages (from-to)431-437
Number of pages7
JournalPhysics in Medicine and Biology
Issue number4
StatePublished - 1987

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging


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