Radiant energy during infrared neural stimulation at the target structure

Claus Peter Richter*, Suhrud Rajguru, Ryan Stafford, Stuart R. Stock

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

5 Scopus citations


Infrared neural stimulation (INS) describes a method, by which an infrared laser is used to stimulate neurons. The major benefit of INS over stimulating neurons with electrical current is its spatial selectivity. To translate the technique into a clinical application it is important to know the energy required to stimulate the neural structure. With this study we provide measurements of the radiant exposure, at the target structure that is required to stimulate the auditory neurons. Flat polished fibers were inserted into scala tympani so that the spiral ganglion was in front of the optical fiber. Angle polished fibers were inserted along scala tympani, and rotating the beveled surface of the fiber allowed the radiation beam to be directed perpendicular to the spiral ganglion. The radiant exposure for stimulation at the modiolus for flat and angle polished fibers averaged 6.78±2.15 mJ/cm2. With the angle polished fibers, a 90° change in the orientation of the optical beam from an orientation that resulted in an INS-evoked maximum response, resulted in a 50% drop in the response amplitude. When the orientation of the beam was changed by 180°, such that it was directed opposite to the orientation with the maxima, minimum response amplitude was observed.

Original languageEnglish (US)
Title of host publicationPhotonic Therapeutics and Diagnostics IX
StatePublished - 2013
EventPhotonic Therapeutics and Diagnostics IX - San Francisco, CA, United States
Duration: Feb 2 2013Feb 7 2013

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
ISSN (Print)1605-7422


OtherPhotonic Therapeutics and Diagnostics IX
Country/TerritoryUnited States
CitySan Francisco, CA


  • Cochlea
  • Hearing
  • Infrared neural stimulation
  • Laser
  • Optical stimulation

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging


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