Radiation pneumonitis following yttrium-90 radioembolization: Case report and literature review

Chadwick L. Wright; Jeff D. Werner; Jerry M. Tran; Vanessa L. Gates; Ali A. Rikabi; Manisha H. Shah; Riad Salem

doi:10.1016/j.jvir.2012.01.059

Radiation pneumonitis following yttrium-90 radioembolization: Case report and literature review

Chadwick L. Wright, Jeff D. Werner, Jerry M. Tran, Vanessa L. Gates, Ali A. Rikabi, Manisha H. Shah, Riad Salem^*

^*Corresponding author for this work

Radiology

Research output: Contribution to journal › Article › peer-review

71 Scopus citations

Abstract

Radiation-induced pneumonitis (RP) is a rare complication of radioembolization with yttrium-90 ( ⁹⁰Y) microspheres. The present report describes a case of RP in a patient with liver metastases from a gastrointestinal stromal tumor after radioembolization with ⁹⁰Y glass microspheres. This patient developed clinical, functional, and radiographic findings consistent with RP, with near-complete pulmonary parenchymal recovery and no clinical evidence of relapse or progressive decline in pulmonary function over a 9-month period. As clinical use of radioembolization expands, rare adverse events such as RP may become more frequent. It is essential that interventional radiologists, radiation/medical oncologists, and nuclear medicine physicians recognize this potential complication.

Original language	English (US)
Pages (from-to)	669-674
Number of pages	6
Journal	Journal of Vascular and Interventional Radiology
Volume	23
Issue number	5
DOIs	https://doi.org/10.1016/j.jvir.2012.01.059
State	Published - May 2012

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine
Radiology Nuclear Medicine and imaging

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/j.jvir.2012.01.059

Cite this

@article{9cde29badd3d4e63ae5214c9a32fce99,

title = "Radiation pneumonitis following yttrium-90 radioembolization: Case report and literature review",

abstract = "Radiation-induced pneumonitis (RP) is a rare complication of radioembolization with yttrium-90 ( 90Y) microspheres. The present report describes a case of RP in a patient with liver metastases from a gastrointestinal stromal tumor after radioembolization with 90Y glass microspheres. This patient developed clinical, functional, and radiographic findings consistent with RP, with near-complete pulmonary parenchymal recovery and no clinical evidence of relapse or progressive decline in pulmonary function over a 9-month period. As clinical use of radioembolization expands, rare adverse events such as RP may become more frequent. It is essential that interventional radiologists, radiation/medical oncologists, and nuclear medicine physicians recognize this potential complication.",

author = "Wright, {Chadwick L.} and Werner, {Jeff D.} and Tran, {Jerry M.} and Gates, {Vanessa L.} and Rikabi, {Ali A.} and Shah, {Manisha H.} and Riad Salem",

year = "2012",

month = may,

doi = "10.1016/j.jvir.2012.01.059",

language = "English (US)",

volume = "23",

pages = "669--674",

journal = "Journal of Vascular and Interventional Radiology",

issn = "1051-0443",

publisher = "Elsevier Inc.",

number = "5",

}

TY - JOUR

T1 - Radiation pneumonitis following yttrium-90 radioembolization

T2 - Case report and literature review

AU - Wright, Chadwick L.

AU - Werner, Jeff D.

AU - Tran, Jerry M.

AU - Gates, Vanessa L.

AU - Rikabi, Ali A.

AU - Shah, Manisha H.

AU - Salem, Riad

PY - 2012/5

Y1 - 2012/5

N2 - Radiation-induced pneumonitis (RP) is a rare complication of radioembolization with yttrium-90 ( 90Y) microspheres. The present report describes a case of RP in a patient with liver metastases from a gastrointestinal stromal tumor after radioembolization with 90Y glass microspheres. This patient developed clinical, functional, and radiographic findings consistent with RP, with near-complete pulmonary parenchymal recovery and no clinical evidence of relapse or progressive decline in pulmonary function over a 9-month period. As clinical use of radioembolization expands, rare adverse events such as RP may become more frequent. It is essential that interventional radiologists, radiation/medical oncologists, and nuclear medicine physicians recognize this potential complication.

AB - Radiation-induced pneumonitis (RP) is a rare complication of radioembolization with yttrium-90 ( 90Y) microspheres. The present report describes a case of RP in a patient with liver metastases from a gastrointestinal stromal tumor after radioembolization with 90Y glass microspheres. This patient developed clinical, functional, and radiographic findings consistent with RP, with near-complete pulmonary parenchymal recovery and no clinical evidence of relapse or progressive decline in pulmonary function over a 9-month period. As clinical use of radioembolization expands, rare adverse events such as RP may become more frequent. It is essential that interventional radiologists, radiation/medical oncologists, and nuclear medicine physicians recognize this potential complication.

UR - http://www.scopus.com/inward/record.url?scp=84860262002&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84860262002&partnerID=8YFLogxK

U2 - 10.1016/j.jvir.2012.01.059

DO - 10.1016/j.jvir.2012.01.059

M3 - Article

C2 - 22525023

AN - SCOPUS:84860262002

SN - 1051-0443

VL - 23

SP - 669

EP - 674

JO - Journal of Vascular and Interventional Radiology

JF - Journal of Vascular and Interventional Radiology

IS - 5

ER -

Radiation pneumonitis following yttrium-90 radioembolization: Case report and literature review

Abstract

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this