Radiation pneumonitis following yttrium-90 radioembolization: Case report and literature review

Chadwick L. Wright, Jeff D. Werner, Jerry M. Tran, Vanessa L. Gates, Ali A. Rikabi, Manisha H. Shah, Riad Salem*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

64 Scopus citations


Radiation-induced pneumonitis (RP) is a rare complication of radioembolization with yttrium-90 ( 90Y) microspheres. The present report describes a case of RP in a patient with liver metastases from a gastrointestinal stromal tumor after radioembolization with 90Y glass microspheres. This patient developed clinical, functional, and radiographic findings consistent with RP, with near-complete pulmonary parenchymal recovery and no clinical evidence of relapse or progressive decline in pulmonary function over a 9-month period. As clinical use of radioembolization expands, rare adverse events such as RP may become more frequent. It is essential that interventional radiologists, radiation/medical oncologists, and nuclear medicine physicians recognize this potential complication.

Original languageEnglish (US)
Pages (from-to)669-674
Number of pages6
JournalJournal of Vascular and Interventional Radiology
Issue number5
StatePublished - May 2012

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine


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