Radiation-Resistant Prostate Cancer and Salvage Prostatectomy

Yousef Al-Shraideh*, Samir V. Sejpal, Joshua J Meeks

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter


One in six men in the Unites States will be diagnosed with prostate cancer accounting for an incidence of 233,000 cases per year. Nearly half of the men that choose treatment will receive radiation therapy (RT), and depending on the aggressiveness of their tumor, an unknown but significant percentage will have radiation refractory cancers. Identifying recurrences post RT remains challenging with limited biomarkers that can identify persistent cancer. In this chapter, we will highlight methods to detect recurrence after RT, and discuss the oncologic and function outcomes of surgical salvage treatment.

Original languageEnglish (US)
Title of host publicationProstate Cancer
Subtitle of host publicationScience and Clinical Practice: Second Edition
PublisherElsevier Inc
Number of pages6
ISBN (Print)9780128000779
StatePublished - Dec 3 2015


  • PSA
  • Prostate cancer
  • Radiation treatment
  • Radical prostatectomy
  • Surgery

ASJC Scopus subject areas

  • Medicine(all)


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