Radical Cystectomy Perioperative Care Redesign

Richard S. Matulewicz*, Jeffrey Brennan, Raj S. Pruthi, Shilajit D. Kundu, Chris M. Gonzalez, Joshua J. Meeks

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

13 Scopus citations


Objective To present an evidence-based review of the perioperative management of the radical cystectomy (RC) patient in the context of a care redesign initiative. Methods A comprehensive review of the key factors associated with perioperative management of the RC patient was completed. PubMed, Medline, and the Cochrane databases were queried via a computerized search. Specific topics were reviewed within the scope of the three major phases of perioperative management: preoperative, intraoperative, and postoperative. Preference was given to evidence from prospective randomized trials, meta-analyses, and systematic reviews. Results Preoperative considerations to improve care in the RC patient should include multi-disciplinary medical optimization, patient education, and formal coordination of care. Efforts to mitigate the risk of malnutrition and reduce postoperative gastrointestinal complications may include carbohydrate loading, protein nutrition supplementation, and avoiding bowel preparation. Intraoperatively, a fluid and opioid sparing protocol may reduce fluid shifts and avoid complications from paralytic ileus. Finally, enhanced recovery protocols including novel medications, early feeding, and multi-modal analgesia approaches are associated with earlier postoperative convalescence. Conclusion RC is a complex and morbid procedure that may benefit from care redesign. Evidence based quality improvement is integral to this process. We hope that this review will help guide further improvement initiatives for RC.

Original languageEnglish (US)
Pages (from-to)1076-1086
Number of pages11
Issue number6
StatePublished - Dec 1 2015

ASJC Scopus subject areas

  • Urology


Dive into the research topics of 'Radical Cystectomy Perioperative Care Redesign'. Together they form a unique fingerprint.

Cite this