Radioembolization in advanced hepatocellular carcinoma

Ahsun Riaz*, Robert J Lewandowski, Riad Salem

*Corresponding author for this work

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

A 68-year-old man with a remote history of alcohol abuse presented with vague abdominal pain. A review of systems suggested the patient had an Eastern CooperativeOncology Group performance status 1 (restriction of strenuous physical activity). There were no physical examination findings of note. Laboratory studies disclosed Child-Pugh A liver status (no ascites; no encephalopathy; total bilirubin, 1 mg/dL; albumin, 3.5 g/dL; and international normalized rato, 1.2). The alpha-fetoprotein was mildly elevated (19.5 ng/mL). Magnetic resonance imaging with contrast disclosed an infiltrative mass with extensivemalignant right and left portal vein thrombosis (Fig 1A) with cavernous transformation of the portal vein. The infiltrative mass (Fig 2A) was biopsied, revealing hepatocellular carcinoma. No distant metastases were found on a bone scintigraphy or computerized tomography scan. Given these features, this patient was classified as Barcelona Clinic for Liver Cancer stage C. The patient was referred for management of advanced hepatocellular carcinoma.

Original languageEnglish (US)
Pages (from-to)1898-1901
Number of pages4
JournalJournal of Clinical Oncology
Volume36
Issue number19
DOIs
StatePublished - Jul 1 2018

Fingerprint

Hepatocellular Carcinoma
alpha-Fetoproteins
Brain Diseases
Liver Neoplasms
Portal Vein
Bilirubin
Ascites
Radionuclide Imaging
Abdominal Pain
Alcoholism
Physical Examination
Albumins
Thrombosis
Tomography
Magnetic Resonance Imaging
Exercise
Neoplasm Metastasis
Bone and Bones
Liver
Cavernous Transformation of Portal Vein

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

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title = "Radioembolization in advanced hepatocellular carcinoma",
abstract = "A 68-year-old man with a remote history of alcohol abuse presented with vague abdominal pain. A review of systems suggested the patient had an Eastern CooperativeOncology Group performance status 1 (restriction of strenuous physical activity). There were no physical examination findings of note. Laboratory studies disclosed Child-Pugh A liver status (no ascites; no encephalopathy; total bilirubin, 1 mg/dL; albumin, 3.5 g/dL; and international normalized rato, 1.2). The alpha-fetoprotein was mildly elevated (19.5 ng/mL). Magnetic resonance imaging with contrast disclosed an infiltrative mass with extensivemalignant right and left portal vein thrombosis (Fig 1A) with cavernous transformation of the portal vein. The infiltrative mass (Fig 2A) was biopsied, revealing hepatocellular carcinoma. No distant metastases were found on a bone scintigraphy or computerized tomography scan. Given these features, this patient was classified as Barcelona Clinic for Liver Cancer stage C. The patient was referred for management of advanced hepatocellular carcinoma.",
author = "Ahsun Riaz and Lewandowski, {Robert J} and Riad Salem",
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Radioembolization in advanced hepatocellular carcinoma. / Riaz, Ahsun; Lewandowski, Robert J; Salem, Riad.

In: Journal of Clinical Oncology, Vol. 36, No. 19, 01.07.2018, p. 1898-1901.

Research output: Contribution to journalArticle

TY - JOUR

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AU - Riaz, Ahsun

AU - Lewandowski, Robert J

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