Radioembolization with 90Y microspheres: Angiographic and technical considerations

Robert J. Lewandowski, Kent T. Sato, Bassel Atassi, Robert K. Ryu, Albert A. Nemcek, Laura Kulik, Jean Francois Geschwind, Ravi Murthy, William Rilling, David Liu, Lourens Bester, Jose Ignacio Bilbao, Andrew S. Kennedy, Reed A. Omary, Riad Salem*

*Corresponding author for this work

Research output: Contribution to journalReview article

197 Citations (Scopus)

Abstract

The anatomy of the mesenteric system and the hepatic arterial bed has been demonstrated to have a high degree of variation. This is important when considering pre-surgical planning, catheterization, and trans-arterial hepatic therapies. Although anatomical variants have been well described, the characterization and understanding of regional hepatic perfusion in the context of radioembolization have not been studied with great depth. The purpose of this review is to provide a thorough discussion and detailed presentation of the angiographic and technical aspects of radioembolization. Normal vascular anatomy, commonly encountered variants, and factors involved in changes to regional perfusion in the presence of liver tumors are discussed. Furthermore, the principles described here apply to all liver-directed transarterial therapies.

Original languageEnglish (US)
Pages (from-to)571-592
Number of pages22
JournalCardioVascular and Interventional Radiology
Volume30
Issue number4
DOIs
StatePublished - Jul 1 2007

Fingerprint

Microspheres
Liver
Anatomy
Perfusion
Catheterization
Blood Vessels
Therapeutics
Neoplasms

Keywords

  • Brachytherapy
  • Embolization
  • Liver cancer
  • Radioembolization
  • SIR-Spheres
  • Selective internal radiation
  • TheraSphere
  • Yttrium-90

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

Cite this

Lewandowski, Robert J. ; Sato, Kent T. ; Atassi, Bassel ; Ryu, Robert K. ; Nemcek, Albert A. ; Kulik, Laura ; Geschwind, Jean Francois ; Murthy, Ravi ; Rilling, William ; Liu, David ; Bester, Lourens ; Bilbao, Jose Ignacio ; Kennedy, Andrew S. ; Omary, Reed A. ; Salem, Riad. / Radioembolization with 90Y microspheres : Angiographic and technical considerations. In: CardioVascular and Interventional Radiology. 2007 ; Vol. 30, No. 4. pp. 571-592.
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Lewandowski, RJ, Sato, KT, Atassi, B, Ryu, RK, Nemcek, AA, Kulik, L, Geschwind, JF, Murthy, R, Rilling, W, Liu, D, Bester, L, Bilbao, JI, Kennedy, AS, Omary, RA & Salem, R 2007, 'Radioembolization with 90Y microspheres: Angiographic and technical considerations', CardioVascular and Interventional Radiology, vol. 30, no. 4, pp. 571-592. https://doi.org/10.1007/s00270-007-9064-z

Radioembolization with 90Y microspheres : Angiographic and technical considerations. / Lewandowski, Robert J.; Sato, Kent T.; Atassi, Bassel; Ryu, Robert K.; Nemcek, Albert A.; Kulik, Laura; Geschwind, Jean Francois; Murthy, Ravi; Rilling, William; Liu, David; Bester, Lourens; Bilbao, Jose Ignacio; Kennedy, Andrew S.; Omary, Reed A.; Salem, Riad.

In: CardioVascular and Interventional Radiology, Vol. 30, No. 4, 01.07.2007, p. 571-592.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Radioembolization with 90Y microspheres

T2 - Angiographic and technical considerations

AU - Lewandowski, Robert J.

AU - Sato, Kent T.

AU - Atassi, Bassel

AU - Ryu, Robert K.

AU - Nemcek, Albert A.

AU - Kulik, Laura

AU - Geschwind, Jean Francois

AU - Murthy, Ravi

AU - Rilling, William

AU - Liu, David

AU - Bester, Lourens

AU - Bilbao, Jose Ignacio

AU - Kennedy, Andrew S.

AU - Omary, Reed A.

AU - Salem, Riad

PY - 2007/7/1

Y1 - 2007/7/1

N2 - The anatomy of the mesenteric system and the hepatic arterial bed has been demonstrated to have a high degree of variation. This is important when considering pre-surgical planning, catheterization, and trans-arterial hepatic therapies. Although anatomical variants have been well described, the characterization and understanding of regional hepatic perfusion in the context of radioembolization have not been studied with great depth. The purpose of this review is to provide a thorough discussion and detailed presentation of the angiographic and technical aspects of radioembolization. Normal vascular anatomy, commonly encountered variants, and factors involved in changes to regional perfusion in the presence of liver tumors are discussed. Furthermore, the principles described here apply to all liver-directed transarterial therapies.

AB - The anatomy of the mesenteric system and the hepatic arterial bed has been demonstrated to have a high degree of variation. This is important when considering pre-surgical planning, catheterization, and trans-arterial hepatic therapies. Although anatomical variants have been well described, the characterization and understanding of regional hepatic perfusion in the context of radioembolization have not been studied with great depth. The purpose of this review is to provide a thorough discussion and detailed presentation of the angiographic and technical aspects of radioembolization. Normal vascular anatomy, commonly encountered variants, and factors involved in changes to regional perfusion in the presence of liver tumors are discussed. Furthermore, the principles described here apply to all liver-directed transarterial therapies.

KW - Brachytherapy

KW - Embolization

KW - Liver cancer

KW - Radioembolization

KW - SIR-Spheres

KW - Selective internal radiation

KW - TheraSphere

KW - Yttrium-90

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U2 - 10.1007/s00270-007-9064-z

DO - 10.1007/s00270-007-9064-z

M3 - Review article

C2 - 17516113

AN - SCOPUS:34548842842

VL - 30

SP - 571

EP - 592

JO - CardioVascular and Interventional Radiology

JF - CardioVascular and Interventional Radiology

SN - 7415-5101

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