Radioembolization with 90Y microspheres: Angiographic and technical considerations

Robert J. Lewandowski, Kent T. Sato, Bassel Atassi, Robert K. Ryu, Albert A. Nemcek, Laura Kulik, Jean Francois Geschwind, Ravi Murthy, William Rilling, David Liu, Lourens Bester, Jose Ignacio Bilbao, Andrew S. Kennedy, Reed A. Omary, Riad Salem*

*Corresponding author for this work

Research output: Contribution to journalReview article

203 Scopus citations

Abstract

The anatomy of the mesenteric system and the hepatic arterial bed has been demonstrated to have a high degree of variation. This is important when considering pre-surgical planning, catheterization, and trans-arterial hepatic therapies. Although anatomical variants have been well described, the characterization and understanding of regional hepatic perfusion in the context of radioembolization have not been studied with great depth. The purpose of this review is to provide a thorough discussion and detailed presentation of the angiographic and technical aspects of radioembolization. Normal vascular anatomy, commonly encountered variants, and factors involved in changes to regional perfusion in the presence of liver tumors are discussed. Furthermore, the principles described here apply to all liver-directed transarterial therapies.

Original languageEnglish (US)
Pages (from-to)571-592
Number of pages22
JournalCardiovascular and Interventional Radiology
Volume30
Issue number4
DOIs
StatePublished - Jul 1 2007

Keywords

  • Brachytherapy
  • Embolization
  • Liver cancer
  • Radioembolization
  • SIR-Spheres
  • Selective internal radiation
  • TheraSphere
  • Yttrium-90

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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    Lewandowski, R. J., Sato, K. T., Atassi, B., Ryu, R. K., Nemcek, A. A., Kulik, L., Geschwind, J. F., Murthy, R., Rilling, W., Liu, D., Bester, L., Bilbao, J. I., Kennedy, A. S., Omary, R. A., & Salem, R. (2007). Radioembolization with 90Y microspheres: Angiographic and technical considerations. Cardiovascular and Interventional Radiology, 30(4), 571-592. https://doi.org/10.1007/s00270-007-9064-z