Radioembolization with 90yttrium microspheres: A state-of-the-art brachytherapy treatment for primary and secondary liver malignancies - Part 1: Technical and methodologic considerations

Riad Salem*, Kenneth G. Thurston

*Corresponding author for this work

Research output: Contribution to journalReview article

439 Scopus citations


Microsphere and particle technology represent the next-generation agents that have formed the basis of interventional oncology, an evolving subspecialty of interventional radiology. One of these platforms, yttrium-90 microspheres, is rapidly being adopted in the medical community as an adjunctive therapeutic tool in the management of primary and secondary liver malignancies. Given the complexity of the treatment algorithm of patients who may be candidates for this therapy and the need for clinical guidance, a comprehensive review of the methodologic and technical considerations was undertaken. This experience is based on more than 900 Y infusions performed over a 5-year period.

Original languageEnglish (US)
Pages (from-to)1251-1278
Number of pages28
JournalJournal of Vascular and Interventional Radiology
Issue number8
StatePublished - Aug 1 2006


ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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