A modification of the methotrexate radioassay kit (supplied by New England Enzyme Center) enabled determination of trimethoprim levels in 5-μl serum samples. An excellent correlation between this assay and high-pressure liquid chromatography assay was found. These preliminary results suggest that with this method rapid determination of trimethoprim levels in very small samples (5 to 10 μl) can be achieved.
|Original language||English (US)|
|Number of pages||2|
|Journal||Journal of Clinical Microbiology|
|State||Published - Jan 1 1985|
ASJC Scopus subject areas
- Microbiology (medical)