Radioenzymatic assay for trimethoprim in very small serum samples

R. Yogev; C. Melick; L. Tan-Pong

doi:10.1128/jcm.21.2.249-250.1985

Radioenzymatic assay for trimethoprim in very small serum samples

R. Yogev, C. Melick, L. Tan-Pong

Pediatrics

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

A modification of the methotrexate radioassay kit (supplied by New England Enzyme Center) enabled determination of trimethoprim levels in 5-μl serum samples. An excellent correlation between this assay and high-pressure liquid chromatography assay was found. These preliminary results suggest that with this method rapid determination of trimethoprim levels in very small samples (5 to 10 μl) can be achieved.

Original language	English (US)
Pages (from-to)	249-250
Number of pages	2
Journal	Journal of clinical microbiology
Volume	21
Issue number	2
DOIs	https://doi.org/10.1128/jcm.21.2.249-250.1985
State	Published - 1985

ASJC Scopus subject areas

Microbiology (medical)

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10.1128/jcm.21.2.249-250.1985

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title = "Radioenzymatic assay for trimethoprim in very small serum samples",

abstract = "A modification of the methotrexate radioassay kit (supplied by New England Enzyme Center) enabled determination of trimethoprim levels in 5-μl serum samples. An excellent correlation between this assay and high-pressure liquid chromatography assay was found. These preliminary results suggest that with this method rapid determination of trimethoprim levels in very small samples (5 to 10 μl) can be achieved.",

author = "R. Yogev and C. Melick and L. Tan-Pong",

year = "1985",

doi = "10.1128/jcm.21.2.249-250.1985",

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AU - Melick, C.

AU - Tan-Pong, L.

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N2 - A modification of the methotrexate radioassay kit (supplied by New England Enzyme Center) enabled determination of trimethoprim levels in 5-μl serum samples. An excellent correlation between this assay and high-pressure liquid chromatography assay was found. These preliminary results suggest that with this method rapid determination of trimethoprim levels in very small samples (5 to 10 μl) can be achieved.

AB - A modification of the methotrexate radioassay kit (supplied by New England Enzyme Center) enabled determination of trimethoprim levels in 5-μl serum samples. An excellent correlation between this assay and high-pressure liquid chromatography assay was found. These preliminary results suggest that with this method rapid determination of trimethoprim levels in very small samples (5 to 10 μl) can be achieved.

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ER -

Radioenzymatic assay for trimethoprim in very small serum samples

Abstract

ASJC Scopus subject areas

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