Radiographic disease severity in chronic rhinosinusitis patients and health care utilization

Mitesh P. Mehta*, Kevin Hur, Caroline P.E. Price, Stephanie Shintani-Smith, Kevin C. Welch, David B. Conley, Robert C. Kern, Bruce K. Tan

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations


Objectives: Chronic rhinosinusitis (CRS) affects approximately 12% of the population and leads to increased health care utilization and indirect costs exceeding $20 billion annually in the United States. The Lund-Mackay score (LMS) measures radiographic disease severity for CRS but poorly correlates with symptom scores. The association between LMS and health care utilization in CRS patients has not yet been investigated. The study aimed to assess the association between health care utilization and CRS radiographic severity using LMS. Methods: CRS patients enrolled in a clinical registry were evaluated. Nasal endoscopy findings and LMS were recorded for patients with sinus CT imaging. Patient symptom scores, demographic characteristics, and health care utilization measures were collected. The relationship between these factors and LMS was examined. Results: A total of 556 patients met inclusion criteria. Mean age was 45.3 years, 53.4% were male, and 41.7% had nasal polyps. There was no difference in sex, smoking history, 22-item Sino-nasal Outcome Test scores, or past medical history factors between patients with high (≥8, n = 410) and low (<8, n = 146) LMS. Among high LMS patients, 73.7% underwent endoscopic sinus surgery (ESS) compared to 55.5% with low LMS (P <.01), and a greater percentage of patients had nasal polyps (49.3% vs 20.5%, P <.01). On multivariable logistic regression, high LMS patients used fewer antibiotic courses (OR: 0.68 [0.51-0.91]), but were more likely to be managed with ESS (OR: 2.28 [1.41-3.73]), and have nasal polyps (OR: 2.11 [1.16-3.93]) compared to low LMS patients. There was no significant difference in the number of steroid courses, over the counter pill use, provider visits, work/school days missed, or symptom duration between the two LMS groups. Conclusion: CRS patients with severe radiographic disease are more likely to have nasal polyps, undergo ESS, and take fewer antibiotic courses. However, there is no association between radiographic disease severity and other measures of health care utilization. Level of Evidence: 2b, individual retrospective cohort study.

Original languageEnglish (US)
Pages (from-to)924-931
Number of pages8
JournalLaryngoscope investigative otolaryngology
Issue number5
StatePublished - Oct 2021


  • Lund-Mackay score
  • SNOT-22
  • chronic rhinosinusitis
  • health care utilization
  • radiographic disease severity

ASJC Scopus subject areas

  • Surgery
  • Otorhinolaryngology


Dive into the research topics of 'Radiographic disease severity in chronic rhinosinusitis patients and health care utilization'. Together they form a unique fingerprint.

Cite this