Radioimmunoassay for MM and BB isoenzymes of creatinine kinase substantiated by clinical application

V. S. Fang, H. W. Cho, H. Y. Meltzer

Research output: Contribution to journalArticlepeer-review

16 Scopus citations

Abstract

The authors developed a radioimmunoassay technique that is highly specific for measuring the MM isoenzyme of creatine kinase. The specificity of the radioimmunoassay for the BB isoenzyme was poor. In patients with treated Duchenne type muscular dystrophy or untreated hypothyroidism, the MM isoenzyme, but not the BB isoenzyme value, was consistently above normal. In the radioimmunoassay for the BB isoenzyme the antisera might cross react with other materials and the inactivated isoenzyme, but not with MM or MB isoenzymes.

Original languageEnglish (US)
Pages (from-to)1898-1902
Number of pages5
JournalClinical chemistry
Volume23
Issue number10
DOIs
StatePublished - 1977

ASJC Scopus subject areas

  • Clinical Biochemistry
  • Biochemistry, medical

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