Radiologically guided percutaneous fine-needle aspiration biopsy of the liver: Retrospective study of 119 cases evaluating diagnostic effectiveness and clinical complications

Ziwen Guo, Daniel F I Kurtycz, Riad Salem, Luis E. De Las Casas, James G. Caya, H. Daniel Hoerl

Research output: Contribution to journalArticlepeer-review

28 Scopus citations

Abstract

We reviewed 119 percutaneous, radiologically guided fine-needle aspirations (FNA) from 114 patients with liver masses to evaluate diagnostic effectiveness and complications of this procedure. Satisfactory material was obtained in 118 cases (99%), of which 78 were diagnosed as positive (66%), three suspicious (2%), five atypical (4%), and 32 (27%) as negative for malignancy. Compared to surgical biopsy (48 cases) and clinical data, the sensitivity and specificity of FNA for malignancy was 95.1% and 100%, respectively, yielding a positive predictive value of 100% and a negative predictive value of 88.8%. Four cytology cases (3.4%) were false-negatives (FN); all were interpretive errors. Four FN surgical biopsies (8.3%) were sampling errors. Minor complications occurred in three cases (2.5%). We conclude that FNA is safe and effective for determining the malignant potential of liver masses and should be the procedure of choice. Our experience suggests that having a pathologist present in the radiology suite provides optimal patient care.

Original languageEnglish (US)
Pages (from-to)283-289
Number of pages7
JournalDiagnostic cytopathology
Volume26
Issue number5
DOIs
StatePublished - May 20 2002

Keywords

  • Biopsy
  • Complications
  • Fine-needle aspiration
  • Liver
  • Neoplasms
  • On-site assessment

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Histology

Fingerprint Dive into the research topics of 'Radiologically guided percutaneous fine-needle aspiration biopsy of the liver: Retrospective study of 119 cases evaluating diagnostic effectiveness and clinical complications'. Together they form a unique fingerprint.

Cite this