Randomized clinical trials in advanced and metastatic colorectal carcinoma

Michael I. D'Angelica*, Margo C. Shoup, Aviram Nissan

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

8 Scopus citations

Abstract

The treatment of advanced colorectal cancer has long been a dilemna for clinicians. After many years of therapy limited to 5-fluorouracil (5-FU)-based chemotherapy, a number of new discoveries have significantly advanced this field in the last decade. The advent of irinotecan has given us hope for a second line chemotherapeutic agent and a possible new combination for first line chemotherapy.

Original languageEnglish (US)
Pages (from-to)173-191
Number of pages19
JournalSurgical Oncology Clinics of North America
Volume11
Issue number1
DOIs
StatePublished - Jan 1 2002

ASJC Scopus subject areas

  • Surgery
  • Oncology

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