Rapid Aqueous Photouncaging by Red Light

Xiaodi Wang, Julia A. Kalow*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

30 Scopus citations


This work describes three new red-photocleavable dyes. The best-performing dye exhibits a quantum yield of 5.7% in 30:70 v/v water/acetonitrile and approximately 80% release of benzoic acid using a 626 nm LED. Photo-orthogonality between this dye and a UV-activated photouncaging group was demonstrated. Additionally, a qualitative comparison between the same pair of dyes in a gel was performed, highlighting the superior penetration depth that can be achieved using the newly reported dye.

Original languageEnglish (US)
Pages (from-to)1716-1719
Number of pages4
JournalOrganic Letters
Issue number7
StatePublished - Apr 6 2018

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry


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