Abstract
This work describes three new red-photocleavable dyes. The best-performing dye exhibits a quantum yield of 5.7% in 30:70 v/v water/acetonitrile and approximately 80% release of benzoic acid using a 626 nm LED. Photo-orthogonality between this dye and a UV-activated photouncaging group was demonstrated. Additionally, a qualitative comparison between the same pair of dyes in a gel was performed, highlighting the superior penetration depth that can be achieved using the newly reported dye.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1716-1719 |
| Number of pages | 4 |
| Journal | Organic Letters |
| Volume | 20 |
| Issue number | 7 |
| DOIs | |
| State | Published - Apr 6 2018 |
Funding
The authors acknowledge Shichen Lian, Chen Wang, and Prof. Emily Weiss (Northwestern) for assistance with quantum yield measurements and the Dichtel laboratory (Northwestern) for use of their UV−vis spectrophotometer. This work was supported by an Institutional Research Grant, IRG-15-173-21, from the American Cancer Society and startup funds from Northwestern University. This work made use of the Integrated Molecular Structure Education and Research Center at Northwestern, which has received support from the NIH (S10-OD021786-01), the NSF (CHE-9871268), the Soft and Hybrid Nanotechnology Experimental (SHyNE) Resource (NSF ECCS-1542205), the State of Illinois, and the International Institute for Nanotechnology. This work was supported by an Institutional Research Grant, IRG-15-173-21, from the American Cancer Society and startup funds from Northwestern University. This work made use of the Integrated Molecular Structure Education and Research Center at Northwestern which has received support from the NIH (S10-OD021786-01), the NSF (CHE-9871268), the Soft and Hybrid Nanotechnology Experimental (SHyNE) Resource (NSF ECCS-1542205), the State of Illinois, and the International Institute for Nanotechnology.
ASJC Scopus subject areas
- Biochemistry
- Physical and Theoretical Chemistry
- Organic Chemistry