Rapid time-resolved magnetic resonance angiography via a multiecho radial trajectory and GraDeS reconstruction

Gregory R. Lee*, Nicole Seiberlich, Jeffrey L. Sunshine, Timothy J. Carroll, Mark A. Griswold

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

16 Scopus citations


Contrast-enhanced magnetic resonance angiography is challenging due to the need for both high spatial and temporal resolution. A multishot trajectory composed of pseudo-random rotations of a single multiecho radial readout was developed. The trajectory is designed to give incoherent aliasing artifacts and a relatively uniform distribution of projections over all time scales. A field map (computed from the same data set) is used to avoid signal dropout in regions of substantial field inhomogeneity. A compressed sensing reconstruction using the GraDeS algorithm was used. Whole brain angiograms were reconstructed at 1-mm isotropic resolution and a 1.1-s frame rate (corresponding to an acceleration factor > 100). The only parameter which must be chosen is the number of iterations of the GraDeS algorithm. A larger number of iterations improves the temporal behavior at cost of decreased image signal-to-noise ratio. The resulting images provide a good depiction of the cerebral vasculature and have excellent arterial/venous separation. Magn Reson Med, 2013. © 2012 Wiley Periodicals, Inc.

Original languageEnglish (US)
Pages (from-to)346-359
Number of pages14
JournalMagnetic resonance in medicine
Issue number2
StatePublished - Feb 2013


  • 4D contrast enhanced angiography
  • GraDeS
  • compressed sensing
  • time-resolved angiography

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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