Rare Middle Mediastinal Paraganglioma Mimicking Metastatic Neuroendocrine Tumor

Christopher K. Mehta, Colin Thomas Gillespie, Xiaoqi Lin, Anjana V Yeldandi, Malcom McAvoy DeCamp Jr, Ankit Bharat*

*Corresponding author for this work

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Mediastinal paragangliomas are rare neural crest derived tumors that may produce symptoms of excess catecholamine production or mass effect. Paragangliomas can histologically mimic neuroendocrine tumors. Further, both can arise in similar locations. We report a patient who presented with a right upper lobe as well as middle mediastinal lesion. Preoperative biopsy as well as intraoperative frozen section of these lesions failed to distinguish between paraganlioma or neuroendocrine tumor, necessitating a right upper lobectomy and complete mediastinal lymphadenectomy. Final pathology revealed carcinoid tumorlets in the right upper lobe and a middle mediastinal paraganglioma.

Original languageEnglish (US)
Pages (from-to)702-705
Number of pages4
JournalAnnals of Thoracic Surgery
Volume100
Issue number2
DOIs
StatePublished - Jan 1 2015

Fingerprint

Paraganglioma
Neuroendocrine Tumors
Carcinoid Tumor
Frozen Sections
Lymph Node Excision
Catecholamines
Pathology
Biopsy

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery
  • Pulmonary and Respiratory Medicine
  • Medicine(all)

Cite this

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abstract = "Mediastinal paragangliomas are rare neural crest derived tumors that may produce symptoms of excess catecholamine production or mass effect. Paragangliomas can histologically mimic neuroendocrine tumors. Further, both can arise in similar locations. We report a patient who presented with a right upper lobe as well as middle mediastinal lesion. Preoperative biopsy as well as intraoperative frozen section of these lesions failed to distinguish between paraganlioma or neuroendocrine tumor, necessitating a right upper lobectomy and complete mediastinal lymphadenectomy. Final pathology revealed carcinoid tumorlets in the right upper lobe and a middle mediastinal paraganglioma.",
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Rare Middle Mediastinal Paraganglioma Mimicking Metastatic Neuroendocrine Tumor. / Mehta, Christopher K.; Gillespie, Colin Thomas; Lin, Xiaoqi; Yeldandi, Anjana V; DeCamp Jr, Malcom McAvoy; Bharat, Ankit.

In: Annals of Thoracic Surgery, Vol. 100, No. 2, 01.01.2015, p. 702-705.

Research output: Contribution to journalArticle

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