Abstract
Mediastinal paragangliomas are rare neural crest derived tumors that may produce symptoms of excess catecholamine production or mass effect. Paragangliomas can histologically mimic neuroendocrine tumors. Further, both can arise in similar locations. We report a patient who presented with a right upper lobe as well as middle mediastinal lesion. Preoperative biopsy as well as intraoperative frozen section of these lesions failed to distinguish between paraganlioma or neuroendocrine tumor, necessitating a right upper lobectomy and complete mediastinal lymphadenectomy. Final pathology revealed carcinoid tumorlets in the right upper lobe and a middle mediastinal paraganglioma.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 702-705 |
| Number of pages | 4 |
| Journal | Annals of Thoracic Surgery |
| Volume | 100 |
| Issue number | 2 |
| DOIs | |
| State | Published - Aug 1 2015 |
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ASJC Scopus subject areas
- Surgery
- Pulmonary and Respiratory Medicine
- Cardiology and Cardiovascular Medicine
Cite this
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Rare Middle Mediastinal Paraganglioma Mimicking Metastatic Neuroendocrine Tumor. / Mehta, Christopher K.; Gillespie, Colin T.; Lin, Xiaoqi; Yeldandi, Anjana; DeCamp, Malcolm; Bharat, Ankit.
In: Annals of Thoracic Surgery, Vol. 100, No. 2, 01.08.2015, p. 702-705.Research output: Contribution to journal › Article
TY - JOUR
T1 - Rare Middle Mediastinal Paraganglioma Mimicking Metastatic Neuroendocrine Tumor
AU - Mehta, Christopher K.
AU - Gillespie, Colin T.
AU - Lin, Xiaoqi
AU - Yeldandi, Anjana
AU - DeCamp, Malcolm
AU - Bharat, Ankit
PY - 2015/8/1
Y1 - 2015/8/1
N2 - Mediastinal paragangliomas are rare neural crest derived tumors that may produce symptoms of excess catecholamine production or mass effect. Paragangliomas can histologically mimic neuroendocrine tumors. Further, both can arise in similar locations. We report a patient who presented with a right upper lobe as well as middle mediastinal lesion. Preoperative biopsy as well as intraoperative frozen section of these lesions failed to distinguish between paraganlioma or neuroendocrine tumor, necessitating a right upper lobectomy and complete mediastinal lymphadenectomy. Final pathology revealed carcinoid tumorlets in the right upper lobe and a middle mediastinal paraganglioma.
AB - Mediastinal paragangliomas are rare neural crest derived tumors that may produce symptoms of excess catecholamine production or mass effect. Paragangliomas can histologically mimic neuroendocrine tumors. Further, both can arise in similar locations. We report a patient who presented with a right upper lobe as well as middle mediastinal lesion. Preoperative biopsy as well as intraoperative frozen section of these lesions failed to distinguish between paraganlioma or neuroendocrine tumor, necessitating a right upper lobectomy and complete mediastinal lymphadenectomy. Final pathology revealed carcinoid tumorlets in the right upper lobe and a middle mediastinal paraganglioma.
UR - http://www.scopus.com/inward/record.url?scp=84938718416&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84938718416&partnerID=8YFLogxK
U2 - 10.1016/j.athoracsur.2014.09.068
DO - 10.1016/j.athoracsur.2014.09.068
M3 - Article
C2 - 26234842
AN - SCOPUS:84938718416
VL - 100
SP - 702
EP - 705
JO - Annals of Thoracic Surgery
JF - Annals of Thoracic Surgery
SN - 0003-4975
IS - 2
ER -