Rasmussen encephalitis: Epilepsia partialis continua secondary to chronic encephalitis

Mary L. Zupanc; Eric G. Handler; Ross L. Levine; Timothy W. Jahn; Gabriele M. ZuRhein; Jack M. Rozental; Robert J. Nickles; Curtis R. Partington

doi:10.1016/0887-8994(90)90008-O

Rasmussen encephalitis: Epilepsia partialis continua secondary to chronic encephalitis

Mary L. Zupanc^*, Eric G. Handler, Ross L. Levine, Timothy W. Jahn, Gabriele M. ZuRhein, Jack M. Rozental, Robert J. Nickles, Curtis R. Partington

^*Corresponding author for this work

Neurology

Research output: Contribution to journal › Article › peer-review

27 Scopus citations

Abstract

Rasmussen encephalitis is a disease consisting of chronic encephalitis with progressive neurologic deficits and focal intractable seizure activity. The etiology is unknown, but pathologic specimens revealed changes consistent with viral encephalitis. Even though neuroimaging techniques, such as positron emission tomography and magnetic resonance imaging, offer the prospect of specific, presurgical diagnostic criteria, the initial diagnosis usually is made on a clinical basis. Treatment modalities, including a wide variety of antiepileptic drug therapies and surgical interventions, may result in significant physical and mental impairments. We summarize the clinical presentation, diagnostic considerations, and different treatment protocols in a patient with this rare and debilitating disorder.

Original language	English (US)
Pages (from-to)	397-401
Number of pages	5
Journal	Pediatric neurology
Volume	6
Issue number	6
DOIs	https://doi.org/10.1016/0887-8994(90)90008-O
State	Published - 1990

ASJC Scopus subject areas

Clinical Neurology
Neurology
Developmental Neuroscience
Pediatrics, Perinatology, and Child Health

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10.1016/0887-8994(90)90008-O

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title = "Rasmussen encephalitis: Epilepsia partialis continua secondary to chronic encephalitis",

abstract = "Rasmussen encephalitis is a disease consisting of chronic encephalitis with progressive neurologic deficits and focal intractable seizure activity. The etiology is unknown, but pathologic specimens revealed changes consistent with viral encephalitis. Even though neuroimaging techniques, such as positron emission tomography and magnetic resonance imaging, offer the prospect of specific, presurgical diagnostic criteria, the initial diagnosis usually is made on a clinical basis. Treatment modalities, including a wide variety of antiepileptic drug therapies and surgical interventions, may result in significant physical and mental impairments. We summarize the clinical presentation, diagnostic considerations, and different treatment protocols in a patient with this rare and debilitating disorder.",

author = "Zupanc, {Mary L.} and Handler, {Eric G.} and Levine, {Ross L.} and Jahn, {Timothy W.} and ZuRhein, {Gabriele M.} and Rozental, {Jack M.} and Nickles, {Robert J.} and Partington, {Curtis R.}",

year = "1990",

doi = "10.1016/0887-8994(90)90008-O",

language = "English (US)",

volume = "6",

pages = "397--401",

journal = "Pediatric neurology",

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TY - JOUR

T1 - Rasmussen encephalitis

T2 - Epilepsia partialis continua secondary to chronic encephalitis

AU - Zupanc, Mary L.

AU - Handler, Eric G.

AU - Levine, Ross L.

AU - Jahn, Timothy W.

AU - ZuRhein, Gabriele M.

AU - Rozental, Jack M.

AU - Nickles, Robert J.

AU - Partington, Curtis R.

PY - 1990

Y1 - 1990

N2 - Rasmussen encephalitis is a disease consisting of chronic encephalitis with progressive neurologic deficits and focal intractable seizure activity. The etiology is unknown, but pathologic specimens revealed changes consistent with viral encephalitis. Even though neuroimaging techniques, such as positron emission tomography and magnetic resonance imaging, offer the prospect of specific, presurgical diagnostic criteria, the initial diagnosis usually is made on a clinical basis. Treatment modalities, including a wide variety of antiepileptic drug therapies and surgical interventions, may result in significant physical and mental impairments. We summarize the clinical presentation, diagnostic considerations, and different treatment protocols in a patient with this rare and debilitating disorder.

AB - Rasmussen encephalitis is a disease consisting of chronic encephalitis with progressive neurologic deficits and focal intractable seizure activity. The etiology is unknown, but pathologic specimens revealed changes consistent with viral encephalitis. Even though neuroimaging techniques, such as positron emission tomography and magnetic resonance imaging, offer the prospect of specific, presurgical diagnostic criteria, the initial diagnosis usually is made on a clinical basis. Treatment modalities, including a wide variety of antiepileptic drug therapies and surgical interventions, may result in significant physical and mental impairments. We summarize the clinical presentation, diagnostic considerations, and different treatment protocols in a patient with this rare and debilitating disorder.

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ER -

Rasmussen encephalitis: Epilepsia partialis continua secondary to chronic encephalitis

Abstract

ASJC Scopus subject areas

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