Rasmussen encephalitis: Epilepsia partialis continua secondary to chronic encephalitis

Mary L. Zupanc*, Eric G. Handler, Ross L. Levine, Timothy W. Jahn, Gabriele M. ZuRhein, Jack M. Rozental, Robert J. Nickles, Curtis R. Partington

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


Rasmussen encephalitis is a disease consisting of chronic encephalitis with progressive neurologic deficits and focal intractable seizure activity. The etiology is unknown, but pathologic specimens revealed changes consistent with viral encephalitis. Even though neuroimaging techniques, such as positron emission tomography and magnetic resonance imaging, offer the prospect of specific, presurgical diagnostic criteria, the initial diagnosis usually is made on a clinical basis. Treatment modalities, including a wide variety of antiepileptic drug therapies and surgical interventions, may result in significant physical and mental impairments. We summarize the clinical presentation, diagnostic considerations, and different treatment protocols in a patient with this rare and debilitating disorder.

Original languageEnglish (US)
Pages (from-to)397-401
Number of pages5
JournalPediatric neurology
Issue number6
StatePublished - Jan 1 1990

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Neurology
  • Developmental Neuroscience
  • Clinical Neurology


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