TY - JOUR
T1 - Rates of suicidal ideation among HIV-infected patients in care in the HIV Outpatient Study 2000–2017, USA
AU - the HOPS Investigators
AU - Durham, Marcus D.
AU - Armon, Carl
AU - Mahnken, Jonathan D.
AU - Novak, Richard M.
AU - Palella, Frank J.
AU - Tedaldi, Ellen
AU - Buchacz, Kate
N1 - Funding Information:
Centers for Disease Control and Prevention (contract nos. 200-2001-00133, 200-2006-18797, 200-2011-41872 and 200-2015-63931)
Publisher Copyright:
© 2020
PY - 2020/5
Y1 - 2020/5
N2 - Background: Suicidal ideation (SI) refers to an individual thinking about, considering or planning suicide. Identifying and characterizing persons with HIV (PWH) at greater risk for SI may lead to better suicide prevention strategies and quality of life improvement. Methods: Using clinical data gathered from medical chart abstraction for HIV Outpatient Study (HOPS) participants from 2000 to 2017, we assessed SI frequency among PWH in care and explored factors associated with the presence of SI diagnoses using linear mixed models analyses. Results: Among 6706 participants, 224 (3.3%) had a charted diagnosis of SI. Among those with SI, median age (interquartile range [IQR]) was 43.4 years [IQR: 38.7–50.3], median (IQR) CD4+ cell count was 439 cells/mm3 (IQR: 237–686), 71.4% were male, 54% were men who have sex with men (MSM), 25.4% heterosexual, and 13.4% persons who inject drugs. In multivariable analysis, persons at increased risk for SI were more likely to be: <50 years old (adjusted rate ratio [aRR] 1.86, 95% confidence interval [95%CI] 1.36–2.53), non-Hispanic/Latino black (aRR 1.75; 95%CI 1.29–2.38), have CD4+ cell count <350 cells/mm3 (aRR 1.32; 95%CI 1.05–1.65), have a viral load ≥50 copies/mL (aRR 1.49; 95%CI 1.12–1.98), have stopped antiretroviral therapy (aRR 1.46; 95%CI 1.10–1.95), have a history of: alcohol dependence (aRR 2.75; 95%CI 1.67–4.52), and drug overdose (aRR 4.09; 95%CI 2.16–7.71). Conclusion: Routine mental health assessment and monitoring are needed in HIV clinical practice to better understand factors associated with SI and to inform the development of preventive interventions.
AB - Background: Suicidal ideation (SI) refers to an individual thinking about, considering or planning suicide. Identifying and characterizing persons with HIV (PWH) at greater risk for SI may lead to better suicide prevention strategies and quality of life improvement. Methods: Using clinical data gathered from medical chart abstraction for HIV Outpatient Study (HOPS) participants from 2000 to 2017, we assessed SI frequency among PWH in care and explored factors associated with the presence of SI diagnoses using linear mixed models analyses. Results: Among 6706 participants, 224 (3.3%) had a charted diagnosis of SI. Among those with SI, median age (interquartile range [IQR]) was 43.4 years [IQR: 38.7–50.3], median (IQR) CD4+ cell count was 439 cells/mm3 (IQR: 237–686), 71.4% were male, 54% were men who have sex with men (MSM), 25.4% heterosexual, and 13.4% persons who inject drugs. In multivariable analysis, persons at increased risk for SI were more likely to be: <50 years old (adjusted rate ratio [aRR] 1.86, 95% confidence interval [95%CI] 1.36–2.53), non-Hispanic/Latino black (aRR 1.75; 95%CI 1.29–2.38), have CD4+ cell count <350 cells/mm3 (aRR 1.32; 95%CI 1.05–1.65), have a viral load ≥50 copies/mL (aRR 1.49; 95%CI 1.12–1.98), have stopped antiretroviral therapy (aRR 1.46; 95%CI 1.10–1.95), have a history of: alcohol dependence (aRR 2.75; 95%CI 1.67–4.52), and drug overdose (aRR 4.09; 95%CI 2.16–7.71). Conclusion: Routine mental health assessment and monitoring are needed in HIV clinical practice to better understand factors associated with SI and to inform the development of preventive interventions.
KW - HIV
KW - Mental health
KW - Suicidal ideation
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U2 - 10.1016/j.ypmed.2020.106011
DO - 10.1016/j.ypmed.2020.106011
M3 - Article
C2 - 32027915
AN - SCOPUS:85082584646
VL - 134
JO - Preventive Medicine
JF - Preventive Medicine
SN - 0091-7435
M1 - 106011
ER -