Abstract
The physiological changes of pregnancy can affect the pharmacokinetics of a drug, thereby affecting its dose requirements. Because pharmacokinetic (PK) studies in pregnant women have rarely been conducted, evidence-based dosing adjustments are seldom available. In particular, despite the fact that the use of antidepressants has become increasingly common, pregnancy-associated PK changes of the selective serotonin reuptake inhibitors (SSRIs) are largely unknown.
Original language | English (US) |
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Pages (from-to) | 31-33 |
Number of pages | 3 |
Journal | Clinical pharmacology and therapeutics |
Volume | 100 |
Issue number | 1 |
DOIs | |
State | Published - Jul 1 2016 |
ASJC Scopus subject areas
- Pharmacology (medical)
- Pharmacology