Real-time 3D echocardiographic quantification of left ventricular volumes: Multicenter study for validation with magnetic resonance imaging

V. Mor-Avi*, C. Jenkins, H. Kühl, H. J. Nesser, T. H. Marwick, A. Franke, C. Ebner, B. H. Freed, R. Steringer-Mascherbauer, H. Pollard, L. Weinert, J. Niel, L. Sugeng, R. M. Lang

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

2 Scopus citations

Abstract

Left ventricular (LV) volumes obtained from RT3DE datasets are underestimated compared to cardiac magnetic resonance (CMR). We sought to study the accuracy and reproducibility of this technique in a multicenter setting, the inter-institutional differences in these variables in relationship with investigators' experience, and the potential sources of underestimation. 92 patients underwent CMR and RT3DE imaging at 4 different institutions. End-systolic and end-diastolic LV volumes correlated highly with CMR values (EDV: r=0.91; ESV: r=0.93), but were 29 and 26% lower. This finding was consistent across participating institutions, with the magnitude of bias being related to experience. Exclusion of trabeculae and mitral valve plane from the CMR reference essentially eliminated the inter-modality bias. In conclusion, LV volumes are underestimated in most patients because RT3DE imaging cannot differentiate between the myocardium and trabeculae.

Original languageEnglish (US)
Title of host publicationComputers in Cardiology 2008, CAR
Pages25-28
Number of pages4
Volume35
DOIs
StatePublished - Dec 1 2008
EventComputers in Cardiology 2008, CAR - Bologna, Italy
Duration: Sep 14 2008Sep 17 2008

Other

OtherComputers in Cardiology 2008, CAR
Country/TerritoryItaly
CityBologna
Period9/14/089/17/08

ASJC Scopus subject areas

  • Computer Science Applications
  • Cardiology and Cardiovascular Medicine

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